1. The Dopaminergic and Non-Dopaminergic Features of Parkinson's Disease

  1. C. Warren Olanow MD, FRCPC1,2,3,
  2. Fabrizio Stocchi MD, PhD4 and
  3. Anthony E. Lang MD, FRCPC5,6,7
  1. C. Warren Olanow MD, FRCPC1,2,3,
  2. Fabrizio Stocchi MD, PhD4 and
  3. Anthony E. Lang MD, FRCPC5,6,7

Published Online: 5 OCT 2011

DOI: 10.1002/9781444397970.ch1

Parkinson's Disease: Non-Motor and Non-Dopaminergic Features

Parkinson's Disease: Non-Motor and Non-Dopaminergic Features

How to Cite

Olanow, C. W., Stocchi, F. and Lang, A. E. (2011) The Dopaminergic and Non-Dopaminergic Features of Parkinson's Disease, in Parkinson's Disease: Non-Motor and Non-Dopaminergic Features (eds C. W. Olanow, F. Stocchi and A. E. Lang), Blackwell Publishing Ltd., Oxford, UK. doi: 10.1002/9781444397970.ch1

Editor Information

  1. 1

    Department of Neurology, Mount Sinai School of Medicine, New York, NY, USA

  2. 2

    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY, USA

  3. 3

    Robert and John M. Bendheim Parkinson's Disease Center, Mount Sinai School of Medicine, New York, NY, USA

  4. 4

    Parkinson's Disease and Movement Disorders Research Centre, Institute for Research and Medical Care, IRCCS San Raffaele Pisana, Rome, Italy

  5. 5

    Division of Neurology, University of Toronto, Toronto, ON, Canada

  6. 6

    Parkinson's Disease Research, University of Toronto, Toronto, ON, Canada

  7. 7

    Movement Disorder Centre, Toronto Western Hospital, Toronto, ON, Canada

Author Information

  1. 1

    Department of Neurology, Mount Sinai School of Medicine, New York, NY, USA

  2. 2

    Department of Neuroscience, Mount Sinai School of Medicine, New York, NY, USA

  3. 3

    Robert and John M. Bendheim Parkinson's Disease Center, Mount Sinai School of Medicine, New York, NY, USA

  4. 4

    Parkinson's Disease and Movement Disorders Research Centre, Institute for Research and Medical Care, IRCCS San Raffaele Pisana, Rome, Italy

  5. 5

    Division of Neurology, University of Toronto, Toronto, ON, Canada

  6. 6

    Parkinson's Disease Research, University of Toronto, Toronto, ON, Canada

  7. 7

    Movement Disorder Centre, Toronto Western Hospital, Toronto, ON, Canada

Publication History

  1. Published Online: 5 OCT 2011
  2. Published Print: 29 JUL 2011

ISBN Information

Print ISBN: 9781405191852

Online ISBN: 9781444397970

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Keywords:

  • Parkinson's disease (PD) - dopaminergic and non-dopaminergic features;
  • PD, age-related neurodegenerative disorder;
  • chronic levodopa therapy - and motor complications;
  • levodopa-induced motor complication mechanism - in PD, not known;
  • non-motor and non-dopaminergic features of PD;
  • non-dopaminergic features of disease - source of disability for individuals;
  • identifying neuroprotective - or disease-modifying therapy;
  • non-dopaminergic features of PD - lack of response, to dopaminergic therapies;
  • non-dopaminergic features, and PD diagnosis - prior to motor features of disease;
  • PD, widespread pathology - involving, more than just nigrostriatal system

Summary

This chapter contains sections titled:

  • The dopamine story

  • Levodopa-induced motor complications

  • The non-motor and non-dopaminergic features of PD

  • Conclusions

  • References