10. Cholestatic and Autoimmune Liver Disease

  1. Pierre-Alain Clavien MD, PhD2 and
  2. James F. Trotter MD3
  1. Ulrich Beuers MD

Published Online: 28 MAR 2012

DOI: 10.1002/9781444398441.ch10

Medical Care of the Liver Transplant Patient, 4th edition

Medical Care of the Liver Transplant Patient, 4th edition

How to Cite

Beuers, U. (2012) Cholestatic and Autoimmune Liver Disease, in Medical Care of the Liver Transplant Patient, 4th edition (eds P.-A. Clavien and J. F. Trotter), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444398441.ch10

Editor Information

  1. 2

    Department of Surgery, Swiss HPB (Hepato-Pancreato-Biliary) and Transplantation Center, University Hospital Zürich Zürich, Switzerland

  2. 3

    Baylor University Medical Center, Dallas, TX, USA

Author Information

  1. Department of Gastroenterology and Hepatology, Academic Medical Center, University of Amsterdam, Amsterdam, The Netherlands

Publication History

  1. Published Online: 28 MAR 2012
  2. Published Print: 10 APR 2012

ISBN Information

Print ISBN: 9781444335910

Online ISBN: 9781444398441



  • primary biliary cirrhosis;
  • primary sclerosing cholangitis;
  • autoimmune hepatitis;
  • overlap


Primary biliary cirrhosis, primary sclerosing cholangitis, and autoimmune hepatitis are the major chronic cholestatic and autoimmune liver diseases of the adult. They commonly have a slowly progressive course and lead to cirrhosis and liver failure when untreated or not adequately responding to medical treatment. This chapter focuses on the management of these diseases based on clinical studies and guidelines published until mid2010.