43. Essentials of Immunohematology

  1. Kandice Kottke-Marchant MD, PhD2,3,4 and
  2. Bruce H. Davis MD5
  1. A. Bradley Eisenbrey MD, PhD

Published Online: 8 AUG 2012

DOI: 10.1002/9781444398595.ch43

Laboratory Hematology Practice

Laboratory Hematology Practice

How to Cite

Eisenbrey, A. B. (2012) Essentials of Immunohematology, in Laboratory Hematology Practice (eds K. Kottke-Marchant and B. H. Davis), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444398595.ch43

Editor Information

  1. 2

    Pathology & Laboratory Medicine Institute, Cleveland, OH, USA

  2. 3

    Department of Pathology, Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA

  3. 4

    Hemostasis and Thrombosis, Department of Clinical Pathology, Cleveland Clinic, Cleveland, OH, USA

  4. 5

    Trillium Diagnostics, LLC, Bangor, ME, USA

Author Information

  1. Gift of Life Michigan, Ann Arbor, MI, USA

Publication History

  1. Published Online: 8 AUG 2012
  2. Published Print: 10 APR 2012

ISBN Information

Print ISBN: 9781405162180

Online ISBN: 9781444398595



  • immunohematology;
  • blood group antigens;
  • anemia;
  • direct antiglobulin test (DAT);
  • indirect antiglobulin test (IAT);
  • transfusion;
  • component therapy;
  • human leukocyte antigens (HLA);
  • erythrocytes;
  • platelets;
  • thrombocytopenia


This chapter covers the specific aspects of immunohematology and transfusion medicine that are relevant to the laboratory practice of hematology. It discusses the major erythrocyte blood group antigens and basic blood bank testing for alloantibodies and autoantibodies. Basic principles of transfusion and component therapy are covered, as are immunohematologic issues with anemia, solid organ transplantation, and bone marrow transplantation.