47. Body Fluid Analysis

  1. Kandice Kottke-Marchant MD, PhD5,6,7 and
  2. Bruce H. Davis MD8
  1. David J. Blomberg MD1,2,
  2. Katherine Galagan MD3 and
  3. Eric F. Glassy MD4

Published Online: 8 AUG 2012

DOI: 10.1002/9781444398595.ch47

Laboratory Hematology Practice

Laboratory Hematology Practice

How to Cite

Blomberg, D. J., Galagan, K. and Glassy, E. F. (2012) Body Fluid Analysis, in Laboratory Hematology Practice (eds K. Kottke-Marchant and B. H. Davis), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444398595.ch47

Editor Information

  1. 5

    Pathology & Laboratory Medicine Institute, Cleveland, OH, USA

  2. 6

    Department of Pathology, Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA

  3. 7

    Hemostasis and Thrombosis, Department of Clinical Pathology, Cleveland Clinic, Cleveland, OH, USA

  4. 8

    Trillium Diagnostics, LLC, Bangor, ME, USA

Author Information

  1. 1

    Pathology and Laboratory Medicine, University of MN, Duluth, MN, USA

  2. 2

    School of Medicine, Duluth, MN, USA

  3. 3

    Virginia Mason Medical Center, Seattle, WA, USA

  4. 4

    Affiliated Pathologists Medical Group, Torrance, CA, USA

Publication History

  1. Published Online: 8 AUG 2012
  2. Published Print: 10 APR 2012

ISBN Information

Print ISBN: 9781405162180

Online ISBN: 9781444398595



  • serous fluids;
  • synovial fluid;
  • cerebrospinal fluid;
  • proficiency testing;
  • transudate/exudates;
  • Papanicolaou stain;
  • Wright–Giemsa stain;
  • polarized light microscopy;
  • critical values


This chapter is organized to reflect workflow in the laboratory and to sequentially address pre-analytic, analytic, and post-analytic aspects of body fluid analysis. An initial section concerns specimen collection issues, progressing to specimen analysis and interpretation. Specific issues concerning proficiency testing requirements for body fluids, examples of testing panels and reflex testing algorithms, critical values, and the role of the pathologist/laboratory director in the overall testing process and interaction with patient care providers are discussed.