51. Point-Of-Care Testing in Hemostasis

  1. Kandice Kottke-Marchant MD, PhD3,4,5 and
  2. Bruce H. Davis MD6
  1. Steve Kitchen PhD1 and
  2. Dianne Kitchen PhD2

Published Online: 8 AUG 2012

DOI: 10.1002/9781444398595.ch51

Laboratory Hematology Practice

Laboratory Hematology Practice

How to Cite

Kitchen, S. and Kitchen, D. (2012) Point-Of-Care Testing in Hemostasis, in Laboratory Hematology Practice (eds K. Kottke-Marchant and B. H. Davis), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444398595.ch51

Editor Information

  1. 3

    Pathology & Laboratory Medicine Institute, Cleveland, OH, USA

  2. 4

    Department of Pathology, Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA

  3. 5

    Hemostasis and Thrombosis, Department of Clinical Pathology, Cleveland Clinic, Cleveland, OH, USA

  4. 6

    Trillium Diagnostics, LLC, Bangor, ME, USA

Author Information

  1. 1

    Sheffield Haemostasis and Thrombosis Centre, Royal Hallamshire Hospital, Sheffield, UK

  2. 2

    UK NEQAS for Blood Coagulation, Sheffield, UK

Publication History

  1. Published Online: 8 AUG 2012
  2. Published Print: 10 APR 2012

ISBN Information

Print ISBN: 9781405162180

Online ISBN: 9781444398595



  • point of care;
  • POC;
  • near-patient testing;
  • NPT;
  • INR;
  • ACT;
  • TEG;
  • ROTEM;
  • PFA


Point-of-care (POC) testing in hemostasis has been in use for more than 50 years with a major expansion in recent years. Tests can be divided into either specific versions of conventional laboratory tests such as the international normalized ratio (INR) or activated partial thromboplastin time (APTT), global tests of hemostasis such as thromboelastography and activated clotting times, and tests of platelet function. Recently there has been a proliferation of devices for determination of the INR for monitoring of oral anticoagulant therapy with testing by many different types of healthcare professional and, more recently, patient self-testing and patient self-management. There has also been an increase in the number of devices in use for POC platelet function testing, in part because of the increased use of different antiplatelet agents. This chapter describes some general principles relevant to POC hemostasis testing as well as reviewing what is available in each of the specific areas of this field.