55. Digital Imaging in Hematology

  1. Kandice Kottke-Marchant MD, PhD2,3,4 and
  2. Bruce H. Davis MD5
  1. Danny Hsu MBBS, FRACP, FRCPA and
  2. Szu-Hee Lee MBBChir, PhD, FRACP, FRCPA

Published Online: 8 AUG 2012

DOI: 10.1002/9781444398595.ch55

Laboratory Hematology Practice

Laboratory Hematology Practice

How to Cite

Hsu, D. and Lee, S.-H. (2012) Digital Imaging in Hematology, in Laboratory Hematology Practice (eds K. Kottke-Marchant and B. H. Davis), Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444398595.ch55

Editor Information

  1. 2

    Pathology & Laboratory Medicine Institute, Cleveland, OH, USA

  2. 3

    Department of Pathology, Cleveland Clinic Lerner College of Medicine, Cleveland, OH, USA

  3. 4

    Hemostasis and Thrombosis, Department of Clinical Pathology, Cleveland Clinic, Cleveland, OH, USA

  4. 5

    Trillium Diagnostics, LLC, Bangor, ME, USA

Author Information

  1. Department of Haematology, St George Hospital, Sydney, NSW, Australia

Publication History

  1. Published Online: 8 AUG 2012
  2. Published Print: 10 APR 2012

ISBN Information

Print ISBN: 9781405162180

Online ISBN: 9781444398595



  • digital imaging;
  • digital photography;
  • virtual slide;
  • virtual microscope;
  • morphology;
  • telepathology;
  • telehematology;
  • proficiency testing;
  • quality assurance;
  • standardization


Advances in electronic imaging, computers, and the Internet have resulted in the rapid emergence of digital imaging in pathology. In laboratory hematology, static, single-frame digital images are widely used in education, automated cell image analyzers, and for research applications. Recently, scanning microscopes that can capture virtual slides at high resolution have enabled the creation of high quality hematology virtual slides. This development has facilitated the use of virtual slides in morphology education, quality assurance, and proficiency testing, and should enhance peer review and consultation in blood and bone marrow morphology. An important issue ahead is the standardization of digital image quality in hematology. With further technologic advances in digital imaging, diagnostic applications, and telehematology could become feasible in the future.