18. Cellular Engineering for the Production of New Blood Components

  1. Jeffrey McCullough MD

Published Online: 8 NOV 2011

DOI: 10.1002/9781444398748.ch18

Transfusion Medicine, Third Edition

Transfusion Medicine, Third Edition

How to Cite

McCullough, J. (2011) Cellular Engineering for the Production of New Blood Components, in Transfusion Medicine, Third Edition, Wiley-Blackwell, Oxford, UK. doi: 10.1002/9781444398748.ch18

Author Information

  1. University of Minnesota, Minneapolis, MN, USA

Publication History

  1. Published Online: 8 NOV 2011
  2. Published Print: 2 DEC 2011

ISBN Information

Print ISBN: 9781444337051

Online ISBN: 9781444398748



  • new blood, cellular engineering;
  • hematopoietic growth factors;
  • novel cellular therapies;
  • IND authorization;
  • marrow, transplantation;
  • bone marrow transplantation;
  • tumor cell purging;
  • umbilical cord blood banking;
  • CFR;
  • quality assurance, GMP process


This chapter contains sections titled:

  • Present generations of blood components

  • Development and production of new blood components

  • Hematopoietic progenitor and stem cells as a blood component

  • General hematopoietic cellular engineering processes

  • Umbilical cord blood banking

  • Adoptive immunotherapy

  • Mesenchymal stem cells

  • Myocardial repair

  • Regulation of cellular engineering

  • Quality assurance and good manufacturing practices for cellular engineering

  • References