Chapter 17. Cardiovascular-related proteins identified in human plasma by the HUPO Plasma Proteome Project Pilot Phase

  1. Prof. Dr. Gilbert S. Omenn
  1. Beniam T. Berhane,
  2. Chenggong Zong,
  3. David A. Liem,
  4. Aaron Huang,
  5. Steven Le,
  6. Ricky D. Edmondson,
  7. Richard C. Jones,
  8. Xin Qiao,
  9. Julian P. Whitelegge,
  10. Peipei Ping and
  11. Thomas M. Vondriska

Published Online: 2 NOV 2006

DOI: 10.1002/9783527609482.ch17

Exploring the Human Plasma Proteome

Exploring the Human Plasma Proteome

How to Cite

Berhane, B. T., Zong, C., Liem, D. A., Huang, A., Le, S., Edmondson, R. D., Jones, R. C., Qiao, X., Whitelegge, J. P., Ping, P. and Vondriska, T. M. (2006) Cardiovascular-related proteins identified in human plasma by the HUPO Plasma Proteome Project Pilot Phase, in Exploring the Human Plasma Proteome (ed G. S. Omenn), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527609482.ch17

Editor Information

  1. Internal Medicine, University of Michigan, A520 MSRB 1 Bldg, 1150 West Medical Center Dr. Ann Arbor, MI 48109–0626, USA

Author Information

  1. Cardiovascular Research Laboratories, Departments of Physiology and Medicine, Division of Cardiology, David Geffen School of Medicine at UCLA, Room 1619, MRL Building, Los Angeles, CA 90095, USA

  1. Originally published in Proteomics 2005, 13, 3520–3530

Publication History

  1. Published Online: 2 NOV 2006
  2. Published Print: 6 OCT 2006

ISBN Information

Print ISBN: 9783527317578

Online ISBN: 9783527609482

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Keywords:

  • human plasma proteome;
  • cardiovascular-related proteins;
  • HUPO plasma proteome project pilot phase;
  • functional analyses;
  • functional implications;
  • organ specific cardiovascular-related proteins in plasma;
  • methodology considerations

Summary

This chapter contains sections titled:

  • Introduction

    • HUPO Plasma Proteome Project pilot phase

    • Need for novel insights into cardiovascular disease

  • Materials and methods

  • Groups of cardiovascular-related proteins

    • Markers of inflammation and CVD

    • Vascular and coagulation proteins

    • Signaling proteins

    • Growth- and differentiation-associated proteins

    • Cytoskeletal proteins

    • Transcription factors

    • Channel and receptor proteins

    • Heart failure- and remodeling-related proteins

  • Functional analyses and implications

    • Organ specific cardiovascular-related proteins in plasma

    • Novel cardiovascular-related proteins identified in plasma

  • Methodology considerations

  • Conclusions and future directions

  • References