Chapter 13. Gene Regulation During Axon and Tissue Regeneration in the Retina of Zebrafish

  1. Dr. Catherina G. Becker and
  2. Dr. Thomas Becker
  1. Marie-Claude Senut,
  2. Blake Fausett,
  3. Matthew Veldman and
  4. Daniel Goldman

Published Online: 5 FEB 2007

DOI: 10.1002/9783527610365.ch13

Model Organisms in Spinal Cord Regeneration

Model Organisms in Spinal Cord Regeneration

How to Cite

Senut, M.-C., Fausett, B., Veldman, M. and Goldman, D. (2006) Gene Regulation During Axon and Tissue Regeneration in the Retina of Zebrafish, in Model Organisms in Spinal Cord Regeneration (eds C. G. Becker and T. Becker), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527610365.ch13

Editor Information

  1. Centre for Neuroscience Research, University of Edinburgh, Summerhall, Edinburgh EH9 1QH, Scotland, UK

Author Information

  1. Department of Biological Chemistry, University of Michigan Molecular and Behavioral Neuroscience Institute, 205 Zina Pitcher Place, Ann Arbor, MI 48109, USA

Publication History

  1. Published Online: 5 FEB 2007
  2. Published Print: 15 DEC 2006

ISBN Information

Print ISBN: 9783527315048

Online ISBN: 9783527610365

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Keywords:

  • gene regulation;
  • axon and tissue regenation in the retina of zebrafish;
  • zebrafish retina;
  • retina injury;
  • optic nerve regeneration;
  • optic nerve lesion

Summary

This chapter contains sections titled:

  • Introduction

  • The Zebrafish Retina

  • Retina Injury

    • Experimental Models of Retinal Injury

    • Gene Regulation in the Injured Zebrafish Retina

      • Phase 1: Programmed Cell Death (Apoptosis) and Immune Response

      • Phase 2: Stem Cell Activation and Proliferation

      • Phase 3: Cellular Migration and Differentiation

    • Approaches to Identifying Transcriptional Regulators in the Injured Retina: The Example of α1-Tubulin

  • Optic Nerve Regeneration

    • Experimental Models of Optic Nerve Regeneration

    • Gene Regulation Following Optic Nerve Lesion

      • Environmental Factors Influencing Fish Optic Nerve Regeneration

      • Intrinsic Mechanisms of Optic Nerve Regeneration

    • Approaches to Identifying Transcriptional Regulators of Optic Nerve Regeneration in Zebrafish: The Example of α1-Tubulin

  • Genetic Strategies for Retinal Regeneration: Perspectives and Challenges

  • Concluding Remarks