Chapter 12. Label-Free Nanowire and Nanotube Biomolecular Sensors for In-Vitro Diagnosis of Cancer and other Diseases

  1. Prof. Dr. Chad A. Mirkin2 and
  2. Prof. Dr. Christof M. Niemeyer3
  1. James R. Heath

Published Online: 19 FEB 2007

DOI: 10.1002/9783527610389.ch12

Nanobiotechnology II: More Concepts and Applications

Nanobiotechnology II: More Concepts and Applications

How to Cite

Heath, J. R. (2007) Label-Free Nanowire and Nanotube Biomolecular Sensors for In-Vitro Diagnosis of Cancer and other Diseases, in Nanobiotechnology II: More Concepts and Applications (eds C. A. Mirkin and C. M. Niemeyer), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527610389.ch12

Editor Information

  1. 2

    Department of Chemistry, International Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA

  2. 3

    Department of Chemistry, University of Dortmund, Chair of Biological and Chemical Microstructuring, Otto-Hahn-Str. 6, 44227 Dortmund, Germany

Author Information

  1. Caltech Chemistry MC 127-72 and the NanoSystems Biology Cancer Center, 1200 East California Blvd., Pasadena, CA 91125, USA

Publication History

  1. Published Online: 19 FEB 2007
  2. Published Print: 26 JAN 2007

ISBN Information

Print ISBN: 9783527316731

Online ISBN: 9783527610389

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Keywords:

  • nanobiotechnology;
  • nanostructures for analytics;
  • label-free nanowire;
  • label-free nanotube biomolecular sensors;
  • in-vitro diagnosis;
  • cancer;
  • diseases;
  • mechanisms of sensing

Summary

This chapter contains sections titled:

  • Overview

  • Background

  • Methods and Current State of the Art

    • Mechanisms of Sensing

    • The Role of the Sensing Environment

    • Nanosensor-Measured Antigen–Analyte On/Off Binding Rates

    • The Nanosensor/Microfluidic Environment

    • Nanosensor Fabrication

    • Biofunctionalizing NW and NT Nanosensors

  • Outlook

  • Acknowledgments

  • References