Chapter 2. Self-Assembling Nanostructures from Coiled-Coil Peptides

  1. Prof. Dr. Chad A. Mirkin3 and
  2. Prof. Dr. Christof M. Niemeyer4
  1. Maxim G. Ryadnov1 and
  2. Derek N. Woolfson2

Published Online: 19 FEB 2007

DOI: 10.1002/9783527610389.ch2

Nanobiotechnology II: More Concepts and Applications

Nanobiotechnology II: More Concepts and Applications

How to Cite

Ryadnov, M. G. and Woolfson, D. N. (2007) Self-Assembling Nanostructures from Coiled-Coil Peptides, in Nanobiotechnology II: More Concepts and Applications (eds C. A. Mirkin and C. M. Niemeyer), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527610389.ch2

Editor Information

  1. 3

    Department of Chemistry, International Institute for Nanotechnology, Northwestern University, 2145 Sheridan Road, Evanston, IL 60208, USA

  2. 4

    Department of Chemistry, University of Dortmund, Chair of Biological and Chemical Microstructuring, Otto-Hahn-Str. 6, 44227 Dortmund, Germany

Author Information

  1. 1

    School of Chemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK

  2. 2

    Department of Biochemistry, University of Bristol, Cantock's Close, Bristol BS8 1TS, UK

Publication History

  1. Published Online: 19 FEB 2007
  2. Published Print: 26 JAN 2007

ISBN Information

Print ISBN: 9783527316731

Online ISBN: 9783527610389

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Keywords:

  • nanobiotechnology;
  • self-assembly;
  • nanoparticles;
  • coiled-coil peptides;
  • peptides in self-assembly;
  • ternary coiled-coil assemblies;
  • nanoscale-linker systems

Summary

This chapter contains sections titled:

  • Background and Overview

    • Introduction: Peptides in Self-Assembly

    • Coiled-Coil Peptides as Building Blocks in Supramolecular Design

    • Coiled-Coil Design in General

  • Methods and Examples

    • Ternary Coiled-Coil Assemblies and Nanoscale-Linker Systems

    • Fibers Assembled Using Linear Peptides

    • Fibers Assembled Using Protein Fragments and Nonlinear Peptide Building Blocks

    • Summary: Pros and Cons of Peptide-Based Assembly of Nanofibers

    • Assembling More-Complex Matrices Using Peptide Assemblies as Linker Struts

      • Programmed Matrices Assembled Exclusively from Coiled-Coil Building Blocks

      • Synthetic Polymer-Coiled-Coil Hybrids

    • Key Techniques

  • Conclusions and Perspectives

  • References