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Carbon Nanotubes for Targeted Cancer Therapy

  1. Reema Zeineldin

Published Online: 15 FEB 2012

DOI: 10.1002/9783527610419.ntls0241

Nanotechnologies for the Life Sciences

Nanotechnologies for the Life Sciences

How to Cite

Zeineldin, R. 2012. Carbon Nanotubes for Targeted Cancer Therapy. Nanotechnologies for the Life Sciences. .

Author Information

  1. Massachusetts College of Pharmacy and Health Sciences, Department of Pharmaceutical Sciences, Worcester, MA, USA

Publication History

  1. Published Online: 15 FEB 2012

Abstract

The sections in this article are

  • Introduction
  • Cancer
  • Conventional Cancer Chemotherapy versus Nanocarrier-Mediated Drug Delivery
    • Challenges with Chemical Compounds as Therapeutic Agents
    • Advantages of Nanocarriers as Drug-Delivery Vehicles
  • Carbon Nanotubes as Drug-Delivery Vehicles
  • Cellular Uptake of CNTs
  • Functionalization of CNTs with Polyethylene Glycol
  • Targeting of Cancers
    • Passive Targeting
    • Active Targeting
    • Trafficking of Targeted Drug-Delivery Vehicles
  • Targeted Cancer Therapy Employing CNTs and a Critique of Current Studies
    • erbB Family Members
    • Folate Receptor α
    • Biotin Receptor
    • Integrins
    • Markers for Lymphomas or Leukemias
    • Disialoganglioside (GD2)
  • Summary and Future Perspective
  • Acknowledgments

Keywords:

  • Carbon nanotubes;
  • single-walled carbon nanotubes;
  • multi-walled carbon nanotubes;
  • cancer;
  • targeting;
  • PEGylation;
  • drug delivery