Chapter 8. The Bipolar Astrocyte: Polarized Features of Astrocytic Glia Underlying Physiology, with Particular Reference to the Blood-Brain Barrier

  1. Prof. Dr. Rolf Dermietzel2,
  2. Prof. Dr. David C. Spray3 and
  3. Prof. Dr. Maiken Nedergaard4
  1. N. Joan Abbott

Published Online: 31 MAY 2007

DOI: 10.1002/9783527611225.ch8

Blood-Brain Barriers: From Ontogeny to Artificial Interfaces, Volume 1

Blood-Brain Barriers: From Ontogeny to Artificial Interfaces, Volume 1

How to Cite

Abbott, N. J. (2006) The Bipolar Astrocyte: Polarized Features of Astrocytic Glia Underlying Physiology, with Particular Reference to the Blood-Brain Barrier, in Blood-Brain Barriers: From Ontogeny to Artificial Interfaces, Volume 1 (eds R. Dermietzel, D. C. Spray and M. Nedergaard), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527611225.ch8

Editor Information

  1. 2

    Department of Neuroanatomy and Molecular Brain Research, Ruhr University Bochum, Universitätsstrasse 150, 44780 Bochum, Germany

  2. 3

    Department of Neuroscience, Albert Einstein College of Medicine, 1410 Pelham Parkway S, Bronx, NY 10464, USA

  3. 4

    School of Medicine and Dentistry, University of Rochester, 601 Elmwood Avenue, Rochester, NY 14642, USA

Author Information

  1. Wolfson Centre for Age Related Diseases, King's College London, Hodgkin Building, Guy's Campus, London, SE1 1UL, UK

Publication History

  1. Published Online: 31 MAY 2007
  2. Published Print: 20 FEB 2006

ISBN Information

Print ISBN: 9783527310883

Online ISBN: 9783527611225

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Keywords:

  • cells of blood-brain interface;
  • bipolar astrocyte;
  • formation of neural tube;
  • origin of neurons;
  • origin of glia;
  • morphology of glial polarity;
  • adult CNS;
  • astrocyte spacing;
  • boundary layers;
  • molecular basis of cell polarity;
  • functional polarity of astrocytes;
  • ependymoglial derivatives;
  • secretory functions of astrocytes;
  • induction of BBB properties in brain endothelium;
  • astrocyte-endothelial signaling

Summary

This chapter contains sections titled:

  • Introduction

  • Formation of the Neural Tube

  • Origin of Neurons and Glia

  • Morphology of Glial Polarity in Adult CNS

  • Astrocyte Spacing and Boundary Layers

  • Origin and Molecular Basis of Cell Polarity

  • Functional Polarity of Astrocytes and Other Ependymoglial Derivatives„

  • Secretory Functions of Astrocytes

  • Induction of BBB Properties in Brain Endothelium

  • Astrocyte-Endothelial Signaling

  • Conclusion

  • References