Chapter 7. Methods of Sample Preparation for Drug Analysis

  1. Petra Gerhards1,
  2. Ulrich Bons2,
  3. Jürgen Sawazki2,
  4. Jörg Szigan3 and
  5. Albert Wertmann3
  1. Petra Gerhards and
  2. Jörg Szigan

Published Online: 29 DEC 2007

DOI: 10.1002/9783527614042.ch7

GC/MS in Clinical Chemistry

GC/MS in Clinical Chemistry

How to Cite

Gerhards, P., Bons, U., Sawazki, J., Szigan, J. and Wertmann, A. (1998) Methods of Sample Preparation for Drug Analysis, in GC/MS in Clinical Chemistry, Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527614042.ch7

Author Information

  1. 1

    Shimadzu Europa GmbH, Albert-Hahn-Straße, 6-10, D-47269, Duisburg

  2. 2

    Apotheke der Rheinischen Landesklinik, Viersen Johannisstraße 70, D-41749, Viersen

  3. 3

    Labor Dr. Lembke und Dr. Lempfrid, An der Wachsfabrik, 25 D-50996, Koln

Publication History

  1. Published Online: 29 DEC 2007
  2. Published Print: 10 DEC 1998

ISBN Information

Print ISBN: 9783527296231

Online ISBN: 9783527614042

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Keywords:

  • drug analysis;
  • liquid-liquid extraction;
  • solid phase extraction;
  • phosphate;
  • phosphate buffer

Summary

This chapter contains sections titled:

  • History of Sample Preparation

  • The Principle of Solid Phase Extraction

  • Liquid-Liquid Extraction (LLE)

  • Comparison of SPE with LLE

  • Quantitative Determination of Derivatized Drugs