Chapter 14. Clostridial Neurotoxins

  1. Klaus Aktories
  1. G. Schiavo and
  2. C. Montecucco

Published Online: 5 JUN 2008

DOI: 10.1002/9783527614615.ch14

Bacterial Toxins: Tools in Cell Biology and Pharmacology

Bacterial Toxins: Tools in Cell Biology and Pharmacology

How to Cite

Schiavo, G. and Montecucco, C. (2008) Clostridial Neurotoxins, in Bacterial Toxins: Tools in Cell Biology and Pharmacology (ed K. Aktories), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527614615.ch14

Publication History

  1. Published Online: 5 JUN 2008
  2. Published Print: 24 APR 1997

ISBN Information

Print ISBN: 9783527308811

Online ISBN: 9783527614615

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Keywords:

  • tetanus neurotoxin;
  • botulinum neurotoxin;
  • clostridial neurotoxins;
  • interneurons;
  • pathophysiological

Summary

The prelims comprise:

  • The Origin of Clostridial Neurotoxins

  • Structure of Clostridial Neurotoxins

  • Mechanism of Action of Clostridial Neurotoxins

  • Clostridial Neurotoxins and the Blockade of Neurotransmitter Release

  • Biomedical Applications of Clostridial Neurotoxins

  • Therapeutic Uses of Botulinum Neurotoxins

  • Concluding Remarks

  • Chemicals