Chapter 7. Molecular Modelling and Simulations of Major Histocompatibility Complex Class I Protein-Peptide Interactions
- Professor Julia M. Goodfellow
Published Online: 19 DEC 2007
DOI: 10.1002/9783527615339.ch7
Copyright © 1995 VCH Verlagsgesellschaft mbH
Book Title
Computer Modelling in Molecular Biology
Additional Information
How to Cite
Thorpe, C. J. and Moss, D. S. (2007) Molecular Modelling and Simulations of Major Histocompatibility Complex Class I Protein-Peptide Interactions, in Computer Modelling in Molecular Biology (ed J. M. Goodfellow), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527615339.ch7
Editor Information
Department of Crystallography, Birkbeck College, University of London, Malet Street, London WClE 7HX, United Kingdom
Publication History
- Published Online: 19 DEC 2007
- Published Print: 27 JUL 1995
ISBN Information
Print ISBN: 9783527300624
Online ISBN: 9783527615339
- Summary
- Chapter
- References
Keywords:
- molecular modelling;
- major histocompatibility complex;
- protein-peptide interactions;
- groove;
- influenza virus peptide
Summary
This chapter contains sections titled:
Introduction
The Structure of the MHC Molecule
The Structure of the Peptide in the Groove
Rationale Used for the Modelling and Simulation of MHC Class I Molecules
General Principles of Modelling MHC Class I-Peptide Interactions
Modelling and Simulation of an Influenza Virus Peptide with the Human MHC Class I Molecule HLA-Aw68
Modelling of an Epstein Barr Virus Nuclear Antigen Peptide with HLA-B27 Sub-Qpe Molecules
Conclusions