Chapter 19. Cellular Assays for Testing Peritoneal Dialysis Bags

  1. Dr. Christoph A Reinhardt
  1. Mary Dawson and
  2. Zara Jabar

Published Online: 8 OCT 2008

DOI: 10.1002/9783527616053.ch19

Alternatives to Animal Testing: New Ways in the Biomedical Sciences, Trends and Progress, Second Edition

Alternatives to Animal Testing: New Ways in the Biomedical Sciences, Trends and Progress, Second Edition

How to Cite

Dawson, M. and Jabar, Z. (1994) Cellular Assays for Testing Peritoneal Dialysis Bags, in Alternatives to Animal Testing: New Ways in the Biomedical Sciences, Trends and Progress, Second Edition (ed C. A. Reinhardt), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527616053.ch19

Editor Information

  1. SIAT Swiss Institute for Alternatives to Animal Testing, Technopark, Pfingstweidstr. 30, CH-8005 Zürich

Publication History

  1. Published Online: 8 OCT 2008
  2. Published Print: 24 FEB 1994

ISBN Information

Print ISBN: 9783527300433

Online ISBN: 9783527616053

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Keywords:

  • inorganic ions;
  • transmonolayer;
  • ultramarine;
  • intracutaneous;
  • peritoneum

Summary

The paper describes a cell culture method for testing plastic dialysis bags for toxic substances which may leak out of them into dialysis fluids. The indices of toxicity used were cellular changes as seen by microscopy, and accelerated fall in the transmonolayer resistance of cell sheets.