Chapter 4.4. Lewis Acid-Mediated Diastereoselective Radical Reactions

  1. Prof. Philippe Renaud1 and
  2. Prof. Mukund P. Sibi2
  1. Brigitte Guérin,
  2. William W. Ogilvie and
  3. Yvan Guindon

Published Online: 26 MAR 2008

DOI: 10.1002/9783527618293.ch22

Radicals in Organic Synthesis

Radicals in Organic Synthesis

How to Cite

Guérin, B., Ogilvie, W. W. and Guindon, Y. (2001) Lewis Acid-Mediated Diastereoselective Radical Reactions, in Radicals in Organic Synthesis (eds P. Renaud and M. P. Sibi), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527618293.ch22

Editor Information

  1. 1

    Universite de Fribourg, Institut de Chimie Organique, Pérolles, CH-1700 Fribourg, Switzerland

  2. 2

    Department of Chemistry, North Dakota State University, Fargo, ND 58105, USA

Publication History

  1. Published Online: 26 MAR 2008
  2. Published Print: 29 MAR 2001

ISBN Information

Print ISBN: 9783527301607

Online ISBN: 9783527618293



  • lewis acid;
  • chiral auxiliaries;
  • tertiary iodide;
  • allylation reactions;
  • monodentate complex formation


The prelims comprise:

  • Introduction

  • Cyclic-Cram Model: the Endocyclic Effect

  • Lewis Acid: Steric and Electronic Enhancements

  • Lewis Acids and Chiral Auxiliaries

  • Conclusion

  • Acknowledgement