Chapter 5.2. Cyclization of Alkoxyl Radicals

  1. Prof. Philippe Renaud1 and
  2. Prof. Mukund P. Sibi2
  1. Jens Hartung

Published Online: 26 MAR 2008

DOI: 10.1002/9783527618293.ch46

Radicals in Organic Synthesis

Radicals in Organic Synthesis

How to Cite

Hartung, J. (2001) Cyclization of Alkoxyl Radicals, in Radicals in Organic Synthesis (eds P. Renaud and M. P. Sibi), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527618293.ch46

Editor Information

  1. 1

    Universite de Fribourg, Institut de Chimie Organique, Pérolles, CH-1700 Fribourg, Switzerland

  2. 2

    Department of Chemistry, North Dakota State University, Fargo, ND 58105, USA

Publication History

  1. Published Online: 26 MAR 2008
  2. Published Print: 29 MAR 2001

ISBN Information

Print ISBN: 9783527301607

Online ISBN: 9783527618293



  • alkoxyl radicals;
  • hydrocarbons;
  • human hormone prostacycline;
  • oxygen-chlorine bond;
  • phenyl tetrahydrofuran


The prelims comprise:

  • Introduction

  • Generation of Alkoxyl Radicals

  • Principles of 4-Penten-1-oxyl Radical Cyclizations—Stereoselectivity, Regioselectivity, and Theoretical Considerations

  • Ring Closure Reactions other than 5-exo-trig Cyclizations

  • Application of Alkoxyl Radical Cyclizations in Synthesis