Chapter 1.7. Decarboxylation via O-Acyl Thiohydroxamates

  1. Prof. Philippe Renaud1 and
  2. Prof. Mukund P. Sibi2
  1. William B. Motherwell and
  2. Christoph Imboden

Published Online: 26 MAR 2008

DOI: 10.1002/9783527618293.ch7

Radicals in Organic Synthesis

Radicals in Organic Synthesis

How to Cite

Motherwell, W. B. and Imboden, C. (2001) Decarboxylation via O-Acyl Thiohydroxamates, in Radicals in Organic Synthesis (eds P. Renaud and M. P. Sibi), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527618293.ch7

Editor Information

  1. 1

    Universite de Fribourg, Institut de Chimie Organique, Pérolles, CH-1700 Fribourg, Switzerland

  2. 2

    Department of Chemistry, North Dakota State University, Fargo, ND 58105, USA

Publication History

  1. Published Online: 26 MAR 2008
  2. Published Print: 29 MAR 2001

ISBN Information

Print ISBN: 9783527301607

Online ISBN: 9783527618293



  • decarboxylation;
  • thiohydroxamates;
  • carbon dioxide;
  • kolbe electrolysis;
  • hydrogen atom donors


The prelims comprise:

  • Introduction

  • The Preparation of O-Acyl Thiohydroxamate Derivatives

  • Functional Group Transformations involving Radical Chain Reactions of O-Acyl Thiohydroxamates

  • Intermolecular Carbon-Carbon Bond Formation by Addition of O-Acyl Thiohydroxamates to Alkenes

  • Carbon-Carbon Bond-Forming Reactions of Barton Esters involving Cyclization

  • Decarboxylative Radical Generation from Precursors Other than Carboxylic Acids

  • Conclusions