Chapter 14. Oligomers and Cellular Toxicity

  1. Jean D. Sipe
  1. Bruce Kagan

Published Online: 23 JAN 2008

DOI: 10.1002/9783527619344.ch14

Amyloid Proteins: The Beta Sheet Conformation and Disease

Amyloid Proteins: The Beta Sheet Conformation and Disease

How to Cite

Kagan, B. (2005) Oligomers and Cellular Toxicity, in Amyloid Proteins: The Beta Sheet Conformation and Disease (ed J. D. Sipe), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527619344.ch14

Editor Information

  1. 8406 North Brook Lane, Bethesda, MD 20814-2615, USA

Publication History

  1. Published Online: 23 JAN 2008
  2. Published Print: 26 JUL 2005

ISBN Information

Print ISBN: 9783527310722

Online ISBN: 9783527619344

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Keywords:

  • oligomers;
  • cellular toxicity;
  • aggregation;
  • hypothesis;
  • oxidative stress

Summary

This chapter contains sections titled:

  • Introduction

  • Aggregation

  • Cellular Mechanisms of Oligomeric Toxicity

  • Loss of Function Hypothesis

  • Receptors for Advanced End-products of Glycation (RAGE) Receptors

  • Oxidative Stress

  • The Channel Hypothesis

  • PrP106–126

  • IAPP

  • ANP

  • SAA

  • AS

  • β2M

  • AL Amyloidosis

  • PG

  • HypF

  • Calcitonin (CT)

  • Lysozyme