Chapter 5. Role of Post-translational Chemical Modifications in Amyloid Fibril Formation

  1. Jean D. Sipe
  1. Melanie R. Nilsson

Published Online: 23 JAN 2008

DOI: 10.1002/9783527619344.ch5

Amyloid Proteins: The Beta Sheet Conformation and Disease

Amyloid Proteins: The Beta Sheet Conformation and Disease

How to Cite

Nilsson, M. R. (2005) Role of Post-translational Chemical Modifications in Amyloid Fibril Formation, in Amyloid Proteins: The Beta Sheet Conformation and Disease (ed J. D. Sipe), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527619344.ch5

Editor Information

  1. 8406 North Brook Lane, Bethesda, MD 20814-2615, USA

Publication History

  1. Published Online: 23 JAN 2008
  2. Published Print: 26 JUL 2005

ISBN Information

Print ISBN: 9783527310722

Online ISBN: 9783527619344

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Keywords:

  • chemical modifications;
  • protein;
  • amyloid fibril;
  • cleavage;
  • destabilization

Summary

This chapter contains sections titled:

  • Introduction

  • Common Modifications that May Play a Significant Role In Vivo

  • Proposed Mechanisms by which Chemical Modifications may Affect Amyloid Deposition

  • Conclusions and Future Directions