Chapter 38. Association Studies of Complex Diseases

  1. Prof. Dr. Thomas Lengauer
  1. Momiao Xiong,
  2. Li Jin

Published Online: 5 FEB 2008

DOI: 10.1002/9783527619368.ch38

Book Title

Bioinformatics - From Genomes to Therapies

Bioinformatics - From Genomes to Therapies

Additional Information

How to Cite

Xiong, M. and Jin, L. (2008) Association Studies of Complex Diseases, in Bioinformatics - From Genomes to Therapies (ed T. Lengauer), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527619368.ch38

Editor Information

  1. Max-Planck-Institute for Informatics, Stuhlsatzenhausweg 85, 66123 Saarbrücken, Germany

Publication History

  1. Published Online: 5 FEB 2008
  2. Published Print: 11 JAN 2007

ISBN Information

Print ISBN: 9783527312788

Online ISBN: 9783527619368

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Keywords:

  • diabetes;
  • manifestations;
  • psychiatric illness;
  • haplotype;
  • disequilibrium

Summary

This chapter contains sections titled:

  • Introduction

  • Linkage Disequilibrium (LD), Haplotype and Association Studies

  • A General Framework for Population-based Association Studies

  • Similarity-based Statistics for Association Studies

  • Generalized T2 Test Statistic

  • Family-based Association Studies

  • Nonlinear Transmission/Disequilibrium Test

  • Perspective of Genome-wide Association Studies

  • References

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