Chapter 14. Clinical Aspects of Tooth Diseases and their Treatment

  1. Prof. Dr. Edmund Bäuerlein
  1. Peter Cängler and
  2. Wolfgang H. Arnold

Published Online: 20 MAR 2008

DOI: 10.1002/9783527619443.ch58

Handbook of Biomineralization: Biological Aspects and Structure Formation

Handbook of Biomineralization: Biological Aspects and Structure Formation

How to Cite

Cängler, P. and Arnold, W. H. (2007) Clinical Aspects of Tooth Diseases and their Treatment, in Handbook of Biomineralization: Biological Aspects and Structure Formation (ed E. Bäuerlein), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527619443.ch58

Editor Information

  1. Max-Planck-Institute for Biochemistry, Department of Membrane Biochemistry, Am Klopferspitz 18 A, 82152 Planegg, Germany

Publication History

  1. Published Online: 20 MAR 2008
  2. Published Print: 25 MAY 2007

ISBN Information

Print ISBN: 9783527316410

Online ISBN: 9783527619443

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Keywords:

  • teeth;
  • evolution;
  • demineralization;
  • remineralization;
  • hard-tissue resorption;
  • hard-tissue apposition;
  • dental caries;
  • periodontal diseases;
  • developmental anomalies;
  • dental trauma

Summary

From an evolutionary point of view, teeth are one of the earliest biomineralization structures of vertebrates. Teeth are unique and different from any other biomineralization outcome of vertebrates. This is reflected in the specialized human odon-togenesis and periodontogenesis and in developmental anomalies, in the clinical appearance and susceptibility to infectious diseases such as dental caries and pe-riodontitis, and finally in the regeneration pattern after traumatic injuries. All pathological features developing during the natural history of dental caries and periodontal diseases, and also the regenerative patterns, are perturbations of the intrinsically conserved pattern of mineralized tissue reactivity. Clinical aspects of tooth diseases and their treatment are characterized by: biomineralization, de-mineralization, remineralization, resorption, and apposition. Hydroxyapatite biomineralization was a major step forward in evolution. The high remodeling potential of hydroxyapatite plays a major role in disease initiation and progression and in the treatment strategies.