Chapter 40. Histone Deacetylase Inhibitors: Development as Anticancer Agents

  1. Prof. Dr. Klaus-Michael Debatin and
  2. PD Dr. Simone Fulda
  1. Paul A. Marks

Published Online: 26 MAY 2008

DOI: 10.1002/9783527619665.ch40

Apoptosis and Cancer Therapy: From Cutting-edge Science to Novel Therapeutic Concepts

Apoptosis and Cancer Therapy: From Cutting-edge Science to Novel Therapeutic Concepts

How to Cite

Marks, P. A. (2006) Histone Deacetylase Inhibitors: Development as Anticancer Agents, in Apoptosis and Cancer Therapy: From Cutting-edge Science to Novel Therapeutic Concepts (eds K.-M. Debatin and S. Fulda), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527619665.ch40

Editor Information

  1. Universitätsklinik für Kinder-und Jugendmedizin, Eythstr. 24, 89075, Ulm

Publication History

  1. Published Online: 26 MAY 2008
  2. Published Print: 6 FEB 2006

ISBN Information

Print ISBN: 9783527312375

Online ISBN: 9783527619665

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Keywords:

  • deacetylase;
  • retinoblastoma;
  • antiproliferative;
  • fibroblasts;
  • phenylbutyrate.

Summary

This chapter contains sections titled:

  • Chromatin Structure

  • HDACs and HATs

  • HAT and HDAC Alterations in Human Cancers

  • HDAC Inhibitors

  • Effects of HDAC Inhibitors

  • Conclusions and Perspectives