Chapter 41. Exploiting Apoptosis Pathways for Glioblastoma Therapy

  1. Prof. Dr. Klaus-Michael Debatin and
  2. PD Dr. Simone Fulda
  1. Johannes Rieger and
  2. Michael Weller

Published Online: 26 MAY 2008

DOI: 10.1002/9783527619665.ch41

Apoptosis and Cancer Therapy: From Cutting-edge Science to Novel Therapeutic Concepts

Apoptosis and Cancer Therapy: From Cutting-edge Science to Novel Therapeutic Concepts

How to Cite

Rieger, J. and Weller, M. (2006) Exploiting Apoptosis Pathways for Glioblastoma Therapy, in Apoptosis and Cancer Therapy: From Cutting-edge Science to Novel Therapeutic Concepts (eds K.-M. Debatin and S. Fulda), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527619665.ch41

Editor Information

  1. Universitätsklinik für Kinder-und Jugendmedizin, Eythstr. 24, 89075, Ulm

Publication History

  1. Published Online: 26 MAY 2008
  2. Published Print: 6 FEB 2006

ISBN Information

Print ISBN: 9783527312375

Online ISBN: 9783527619665

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Keywords:

  • glioblastoma therapy;
  • temozolomide;
  • adenoviruses;
  • malignancies;
  • oligonucleotides

Summary

This chapter contains sections titled:

  • Introduction

  • Activating the p53 pathway

  • Overcoming IAP-mediated Protection from Apoptosis

  • Modulating Bcl-2 Family Member Activity

  • Targeting Growth Factor-dependent Signaling Pathways

  • Death receptors (DRs)

  • Conclusion