Chapter 7. Omi/HtrA2: A Mitochondrial Serine Protease Regulating Cellular Life and Death

  1. Prof. Dr. Klaus-Michael Debatin and
  2. PD Dr. Simone Fulda
  1. Yasuyuki Suzuki and
  2. Ryosuke Takahashi

Published Online: 26 MAY 2008

DOI: 10.1002/9783527619665.ch7

Apoptosis and Cancer Therapy: From Cutting-edge Science to Novel Therapeutic Concepts

Apoptosis and Cancer Therapy: From Cutting-edge Science to Novel Therapeutic Concepts

How to Cite

Suzuki, Y. and Takahashi, R. (2006) Omi/HtrA2: A Mitochondrial Serine Protease Regulating Cellular Life and Death, in Apoptosis and Cancer Therapy: From Cutting-edge Science to Novel Therapeutic Concepts (eds K.-M. Debatin and S. Fulda), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527619665.ch7

Editor Information

  1. Universitätsklinik für Kinder-und Jugendmedizin, Eythstr. 24, 89075, Ulm

Publication History

  1. Published Online: 26 MAY 2008
  2. Published Print: 6 FEB 2006

ISBN Information

Print ISBN: 9783527312375

Online ISBN: 9783527619665

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Keywords:

  • proteases;
  • inhibitors;
  • catalysis;
  • transmembrane segment;
  • mitochondria

Summary

This chapter contains sections titled:

  • Introduction

  • Structure and Properties of Omi/HtrA2

  • Cell Death Regulation by Omi/HtrA2

  • Omi/HtrA2 Mutant Mice

  • Omi/HtrA2 and Cancer Therapy

  • Conclusions