Chapter 13. pDC: From Plasmacytoid Dendritic Cell Precursors to Professional Type 1 Interferon-producing Cells

  1. PD. Dr. Manfred B. Lutz1,
  2. Prof. Dr. Nikolaus Romani2 and
  3. Prof. Dr. Alexander Steinkasserer1
  1. Yong-Jun Liu,
  2. Holger Kanzler,
  3. Yui-Hsi Wang,
  4. Yi-Hong Wang,
  5. Michel Gilliet,
  6. Wei Cao and
  7. Tomoki Ito

Published Online: 26 MAR 2008

DOI: 10.1002/9783527619696.ch13

Handbook of Dendritic Cells: Biology, Diseases, and Therapies

Handbook of Dendritic Cells: Biology, Diseases, and Therapies

How to Cite

Liu, Y.-J., Kanzler, H., Wang, Y.-H., Wang, Y.-H., Gilliet, M., Cao, W. and Ito, T. (2006) pDC: From Plasmacytoid Dendritic Cell Precursors to Professional Type 1 Interferon-producing Cells, in Handbook of Dendritic Cells: Biology, Diseases, and Therapies (eds M. B. Lutz, N. Romani and A. Steinkasserer), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527619696.ch13

Editor Information

  1. 1

    Department of Dermatology, University Hospital of Erlangen, Hartmannstr. 14, 91052 Erlangen, Germany

  2. 2

    Department of Dermatology, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Germany

Publication History

  1. Published Online: 26 MAR 2008
  2. Published Print: 6 FEB 2006

ISBN Information

Print ISBN: 9783527311095

Online ISBN: 9783527619696

SEARCH

Keywords:

  • plasmacytoid;
  • morphology;
  • monkey;
  • isolation;
  • cross-priming

Summary

This chapter contains sections titled:

  • Introduction

  • Isolation and Characterization of pDCs/IPCs

  • pDC/IPC Development

  • Localization, Migration, and Lifespan of pDCs/IPCs

  • Innate Immune Response by pDCs/IPCs

  • Regulation of T-cell-mediated Immune Responses by pDCs/IPCs

  • pDCs/IPCs Regulate the Function of Conventional Myeloid DC by Type 1 IFN

  • Regulation of NK Cell Function by pDCs/IPCs

  • Regulation of B-cell Function by pDCs/IPCs

  • pDCs/IPCs and Human Diseases

  • Conclusion