Chapter 20. The Plasticity of Dendritic Cells Populations in Promoting Th-cell Responses

  1. PD. Dr. Manfred B. Lutz1,
  2. Prof. Dr. Nikolaus Romani2 and
  3. Prof. Dr. Alexander Steinkasserer1
  1. André Boonstra,
  2. Giorgio Trinchieri and
  3. Anne O'Garra

Published Online: 26 MAR 2008

DOI: 10.1002/9783527619696.ch20

Handbook of Dendritic Cells: Biology, Diseases, and Therapies

Handbook of Dendritic Cells: Biology, Diseases, and Therapies

How to Cite

Boonstra, A., Trinchieri, G. and O'Garra, A. (2006) The Plasticity of Dendritic Cells Populations in Promoting Th-cell Responses, in Handbook of Dendritic Cells: Biology, Diseases, and Therapies (eds M. B. Lutz, N. Romani and A. Steinkasserer), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527619696.ch20

Editor Information

  1. 1

    Department of Dermatology, University Hospital of Erlangen, Hartmannstr. 14, 91052 Erlangen, Germany

  2. 2

    Department of Dermatology, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Germany

Publication History

  1. Published Online: 26 MAR 2008
  2. Published Print: 6 FEB 2006

ISBN Information

Print ISBN: 9783527311095

Online ISBN: 9783527619696

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Keywords:

  • plasticity;
  • th-cell populations;
  • Th2 cells;
  • interaction;
  • co-stimulators

Summary

This chapter contains sections titled:

  • Effector Th-cell Populations

  • Factors Inducing the Development of Th1 or Th2 Cells

  • Opposing Concepts:Pre-programmed versus Flexible DC Direct Th-cell Development

  • Differential TLR Expression by Distinct Dendritic Cell Populations

  • Modulation of IL-12p70 or IFN-α Production

  • Factors Responsible for Driving Th2-cell Development

  • Modulation by Tissue Factors

  • Concluding Remarks