Chapter 61. Biodegradability and Silatrane Effect Mechanism

  1. Prof. Dr. Norbert Auner2 and
  2. Prof. Dr. Johann Weis3
  1. Evgenii Ofitserov,
  2. Valerii D'Yakov and
  3. Maksud Rasulov

Published Online: 5 MAY 2008

DOI: 10.1002/9783527619924.ch61

Organosilicon Chemistry V: From Molecules to Materials

Organosilicon Chemistry V: From Molecules to Materials

How to Cite

Ofitserov, E., D'Yakov, V. and Rasulov, M. (2003) Biodegradability and Silatrane Effect Mechanism, in Organosilicon Chemistry V: From Molecules to Materials (eds N. Auner and J. Weis), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527619924.ch61

Editor Information

  1. 2

    Department of Inorganic Chemistry, University of Frankfurt, Marie-Curie-Straße 11, 60439 Frankfurt am Main, Germany

  2. 3

    Consortium of Electrochemical Industry GmbH, Zielstattstraße 20, 81379 Munich, Germany

Author Information

  1. Federal State Unitary Enterprise State Research Institute for Chemistry and Technology of Organoelement Compounds, 38 Shosse Entuziastov, Moscow, 111123 Russia Tel.: +7095 273 6323 — Fax: +7095 913 2538

Publication History

  1. Published Online: 5 MAY 2008
  2. Published Print: 26 SEP 2003

ISBN Information

Print ISBN: 9783527306701

Online ISBN: 9783527619924

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Keywords:

  • silatranes;
  • pharmacokinetics;
  • hepatoprotection effect

Summary

The degradation rate of biologically active hypervalent silicon and germanium compounds (atranes) was investigated under various pH conditions. Stimulating effects on proliferation and reparation processes in experimental animals were demonstrated.