10. Preclinical Testing of Antibodies: Pharmacology, Kinetics and Immunogenicity

  1. Prof. Dr. H.-J. Rehm2,
  2. Dr. G. Reed3
  1. Roly Foulkes,
  2. Sue Stephens

Published Online: 20 MAR 2008

DOI: 10.1002/9783527620869.ch10

Book Title

Biotechnology: A: Recombinant Proteins, Monoclonal Antibodies, and Therapeutic Genes, Volume 5a, Second Edition

Biotechnology: A: Recombinant Proteins, Monoclonal Antibodies, and Therapeutic Genes, Volume 5a, Second Edition

Additional Information

How to Cite

Foulkes, R. and Stephens, S. (2008) Preclinical Testing of Antibodies: Pharmacology, Kinetics and Immunogenicity, in Biotechnology: A: Recombinant Proteins, Monoclonal Antibodies, and Therapeutic Genes, Volume 5a, Second Edition (eds H.-J. Rehm and G. Reed), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527620869.ch10

Editor Information

  1. 2

    Institut für Mikrobiologie, Universität Münster, Corrensstraße 3, D-48149 Münster, FRG

  2. 3

    1029 N. Jackson St., #501-A, Milwaukee, WI 53202-3226, USA

Author Information

  1. Slough, UK

Publication History

  1. Published Online: 20 MAR 2008
  2. Published Print: 26 NOV 1998

ISBN Information

Print ISBN: 9783527283156

Online ISBN: 9783527620869

SEARCH

CHAPTER TOOLS

Get PDF (1709K)

Keywords:

  • demonstration;
  • recombinant;
  • immunogenicity;
  • immunoassay;
  • neutralization

Summary

The prelims comprise:

  • Introduction

  • Development of Assays

  • Product Selection

  • Preclinical Determination of Activity

  • Pharmacokinetics

  • Immunogenicity

  • Summary

Get PDF (1709K)