14. An Engineered Human Antibody for Chronic Therapy: CDP571

  1. Prof. Dr. H.-J. Rehm2,
  2. Dr. G. Reed3
  1. Mark Sopwith,
  2. Sue Stephens

Published Online: 20 MAR 2008

DOI: 10.1002/9783527620869.ch14

Biotechnology: A: Recombinant Proteins, Monoclonal Antibodies, and Therapeutic Genes, Volume 5a, Second Edition

Biotechnology: A: Recombinant Proteins, Monoclonal Antibodies, and Therapeutic Genes, Volume 5a, Second Edition

How to Cite

Sopwith, M. and Stephens, S. (2008) An Engineered Human Antibody for Chronic Therapy: CDP571, in Biotechnology: A: Recombinant Proteins, Monoclonal Antibodies, and Therapeutic Genes, Volume 5a, Second Edition (eds H.-J. Rehm and G. Reed), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527620869.ch14

Editor Information

  1. 2

    Institut für Mikrobiologie, Universität Münster, Corrensstraße 3, D-48149 Münster, FRG

  2. 3

    1029 N. Jackson St., #501-A, Milwaukee, WI 53202-3226, USA

Author Information

  1. Slough, UK

Publication History

  1. Published Online: 20 MAR 2008
  2. Published Print: 26 NOV 1998

ISBN Information

Print ISBN: 9783527283156

Online ISBN: 9783527620869

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Keywords:

  • dysfunction;
  • destruction;
  • exacerbations;
  • proliferation;
  • neutralizing

Summary

The prelims comprise:

  • Introduction

  • Generation of Engineered Human Antibody, CDP571

  • Preclinical Studies with CDP571 in Non-Human Primates

  • Studies with CDP571 in Humans

  • Conclusions