4. In vitro Folding of Inclusion Body Proteins on an Industrial Scale
- Prof. Dr. H.-J. Rehm2,
- Dr. G. Reed3
Published Online: 20 MAR 2008
DOI: 10.1002/9783527620869.ch4
Copyright © 1999 WILEY-VCH Verlag GmbH
Book Title
Biotechnology: A: Recombinant Proteins, Monoclonal Antibodies, and Therapeutic Genes, Volume 5a, Second Edition
Additional Information
How to Cite
Rudolph, R., Lilie, H. and Schwarz, E. (2008) In vitro Folding of Inclusion Body Proteins on an Industrial Scale, in Biotechnology: A: Recombinant Proteins, Monoclonal Antibodies, and Therapeutic Genes, Volume 5a, Second Edition (eds H.-J. Rehm and G. Reed), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527620869.ch4
Editor Information
- 2
Institut für Mikrobiologie, Universität Münster, Corrensstraße 3, D-48149 Münster, FRG
- 3
1029 N. Jackson St., #501-A, Milwaukee, WI 53202-3226, USA
Publication History
- Published Online: 20 MAR 2008
- Published Print: 26 NOV 1998
ISBN Information
Print ISBN: 9783527283156
Online ISBN: 9783527620869
- Summary
- Chapter
- References
Keywords:
- intervention;
- characterize;
- mechanistic;
- fermentation;
- concentrations
Summary
The prelims comprise:
Introduction
Inclusion Body Formation
Cell Lysis and Inclusion Body Isolation
Solubilization of the Inclusion Bodies
In vitro Folding
Prevention of Inclusion Body Formation by Coexpression of Chaperones or Folding Catalysts
Conclusions