6. Advances in the Molecular Genetics of β-Lactam Antibiotic Biosynthesis
- Prof. Dr. H.-J. Rehm5,
- Dr. G. Reed6
Published Online: 28 MAY 2008
DOI: 10.1002/9783527620890.ch6
Copyright © 1997 VCH Verlagsgesellschaft mbH
Book Title
Biotechnology: Products of Secondary Metabolism, Volume 7, Second Edition
Additional Information
How to Cite
Skatrud, P. L., Schwecke, T., Van Liempt, H. and Tobin, M. B. (2008) Advances in the Molecular Genetics of β-Lactam Antibiotic Biosynthesis, in Biotechnology: Products of Secondary Metabolism, Volume 7, Second Edition (eds H.-J. Rehm and G. Reed), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527620890.ch6
Editor Information
- 5
Institut für Mikrobiologie, Universität, Münster, Corrensstraße 3, D-48149 Münster, FRG
- 6
1914 N. Prospect Ave.,#61, Milwaukee, WI 53202-1401, USA
Publication History
- Published Online: 28 MAY 2008
- Published Print: 24 APR 1997
ISBN Information
Print ISBN: 9783527283170
Online ISBN: 9783527620890
- Summary
- Chapter
- References
Keywords:
- biosynthesis;
- enzymes;
- penicillin;
- acyltransferase;
- penicillin
Summary
The chapter contains sections titled:
Introduction
Organisms which Produce β-Lactam Antibiotics
Biosynthesis of β-Lactam Antibiotics
Development of Genetic Transformation Systems
Enzymes Involved in Penicillin Biosynthesis
Cloning of the Genes Involved in the Biosynthesis of Penicillin G, Cephalosporin C, and Cephamycin C
Clustering of β-Lactam Biosynthetic Genes
Compartmentalization of β-Lactam Biosynthetic Enzymes
Evolution of the β-Lactam Biosynthetic Pathway: The Horizontal Transfer Hypothesis
β-Lactam Antibiotics and Recombinant DNA Technology: Practical Applications
Regulation of β-Lactam Biosynthetic Gene Expression
Summary