7. Regioselective Oxidation of Aminosorbitol with Gluconobacter oxydans, Key Reaction in the Industrial 1-Deoxynojirimycin Synthesis

  1. H.-J. Rehm2,
  2. G. Reed3
  1. Michael Schedel

Published Online: 20 MAR 2008

DOI: 10.1002/9783527620913.ch7

Biotechnology: Biotransformations II, Volume 8b, Second Edition, Second Edition

Biotechnology: Biotransformations II, Volume 8b, Second Edition, Second Edition

How to Cite

Schedel, M. (2008) Regioselective Oxidation of Aminosorbitol with Gluconobacter oxydans, Key Reaction in the Industrial 1-Deoxynojirimycin Synthesis, in Biotechnology: Biotransformations II, Volume 8b, Second Edition, Second Edition (eds H.-J. Rehm and G. Reed), Wiley-VCH Verlag GmbH, Weinheim, Germany. doi: 10.1002/9783527620913.ch7

Editor Information

  1. 2

    Institut für Mikrobiologie, Universität, Münster, Corrensstraße 3, D-48149 Münster

  2. 3

    2131 N. Summit Ave., Apartment #304, Milwaukee, WI 53202-1347, USA

Author Information

  1. Wuppertal, Germany

Publication History

  1. Published Online: 20 MAR 2008
  2. Published Print: 13 APR 2000

ISBN Information

Print ISBN: 9783527283248

Online ISBN: 9783527620913

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Keywords:

  • therapeutic;
  • enzyme;
  • inhibitor;
  • purification;
  • structurally

Summary

This chapter contains sections titled:

  • Introduction

  • Nojirimycin, 1-Deoxynojirimycin, and Miglitol

  • Three Routes to Produce 1-Deoxynojirimycin

  • Concept for a Combined Biotechnological-Chemical Synthesis of 1-Deoxynojirimycin

  • Oxidation of 1-Amino-1-Deoxy-D-Sorbitol by Gluconobacter oxydans

  • Biotransformation of N-Formyl-1-Amino-1-Deoxy-D-Sorbitol on the Industrial Scale

  • Fermentative Production of Gluconobacter oxydans Cells on the Industrial Scale

  • Conclusions and Outlook

  • References