Chapter 1. Cellular Energy Metabolism and Integrated Oxidative Phosphorylation

  1. Prof. Valdur Saks3,4,5
  1. Xavier M. Leverve4,
  2. Nellie Taleux1,
  3. Roland Favier4,
  4. Cécile Batandier1,
  5. Dominique Detaille1,
  6. Anne Devin2,
  7. Eric Fontaine4,
  8. Michel Rigoulet2

Published Online: 22 NOV 2007

DOI: 10.1002/9783527621095.ch1

Molecular System Bioenergetics: Energy for Life

Molecular System Bioenergetics: Energy for Life

How to Cite

Leverve, X. M., Taleux, N., Favier, R., Batandier, C., Detaille, D., Devin, A., Fontaine, E. and Rigoulet, M. (2007) Cellular Energy Metabolism and Integrated Oxidative Phosphorylation, in Molecular System Bioenergetics: Energy for Life (ed V. Saks), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527621095.ch1

Editor Information

  1. 3

    J. Fourier University, Laboratory of Bioenergetics, 2280 rue de la Piscine, 38041 Grenoble Cedex 9, France

  2. 4

    Université Joseph Fourier, Bioénergétique Fondamentale et Appliquée, INSERM U884, BP 53X, 38041 Grenoble Cedex, France

  3. 5

    National Institute of Chemical and Biological Physics, Laboratory of Bioenergetics, Akadeemia tee 23, 12618 Tallinn, Estonia

Author Information

  1. 1

    Université Joseph Fourier, Bioénergétique Fondamentale et Appliquée, INSERM E-0221, BP 53X, 38041 Grenoble Cedex, France

  2. 2

    Université de Bordeaux 2, Institut de Biochimie et de Génétique Cellulaires du CNRS, 1 Rue Camille Saint Saëns, 33077 Bordeaux Cedex, France

  3. 4

    Université Joseph Fourier, Bioénergétique Fondamentale et Appliquée, INSERM U884, BP 53X, 38041 Grenoble Cedex, France

Publication History

  1. Published Online: 22 NOV 2007
  2. Published Print: 19 SEP 2007

ISBN Information

Print ISBN: 9783527317875

Online ISBN: 9783527621095

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Keywords:

  • molecular system bioenergetics;
  • biological oxidation;
  • basic principles;
  • organization;
  • dynamics;
  • cellular energetics;
  • integrated oxidative phosphorylation

Summary

This chapter contains sections titled:

  • Abstract

  • Introduction

  • Membrane Transport and Initial Activation

  • Cytosolic Pathway

  • Mitochondrial Transport and Metabolism

  • Respiratory Chain and Oxidative Phosphorylation

  • Electron Supply

  • Reducing Power Shuttling Across the Mitochondrial Membrane

  • Electron Transfer in the Respiratory Chain: Prominent Role of Complex I in the Regulation of the Nature of Substrate

  • Modulation of Oxidative Phosphorylation by Respiratory Chain Slipping and Proton Leak

  • The Nature of Cellular Substrates Interferes with the Metabolic Consequences of Uncoupling

  • Dynamic Supramolecular Arrangement of Respiratory Chain and Regulation of Oxidative Phosphorylation

  • References