Chapter 17. AMPK and the Metabolic Syndrome

  1. Prof. Valdur Saks3,4,5
  1. Benoit Viollet1,
  2. Fabrizio Andreelli2

Published Online: 22 NOV 2007

DOI: 10.1002/9783527621095.ch17

Molecular System Bioenergetics: Energy for Life

Molecular System Bioenergetics: Energy for Life

How to Cite

Viollet, B. and Andreelli, F. (2007) AMPK and the Metabolic Syndrome, in Molecular System Bioenergetics: Energy for Life (ed V. Saks), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527621095.ch17

Editor Information

  1. 3

    J. Fourier University, Laboratory of Bioenergetics, 2280 rue de la Piscine, 38041 Grenoble Cedex 9, France

  2. 4

    Université Joseph Fourier, Bioénergétique Fondamentale et Appliquée, INSERM U884, BP 53X, 38041 Grenoble Cedex, France

  3. 5

    National Institute of Chemical and Biological Physics, Laboratory of Bioenergetics, Akadeemia tee 23, 12618 Tallinn, Estonia

Author Information

  1. 1

    Université Paris 5, Department of Endocrinology, Metabolism, and Cancer Institut Cochin, INSERM U567, CNRS UMR 8104, 24 Rue du Faubourg Saint-Jacques, 75014 Paris, France

  2. 2

    Bichat Claude Bernard Hospital, Diabetology-Endocrinology-Nutrion Department, 46 Rue Henri Huchard, 75877 Paris Cedex 18, France

Publication History

  1. Published Online: 22 NOV 2007
  2. Published Print: 19 SEP 2007

ISBN Information

Print ISBN: 9783527317875

Online ISBN: 9783527621095

SEARCH

Keywords:

  • applied molecular system bioenergetics;
  • AMPK;
  • metabolic syndrome;
  • pathophysiology;
  • management of metabolic syndrome

Summary

This chapter contains sections titled:

  • Abstract

  • Defining the Metabolic Syndrome

  • Pathophysiology of the Metabolic Syndrome

  • AMPK as a Strong Determinant of the Metabolic Syndrome

    • AMPK in the Control of Whole-body Insulin Sensitivity

    • AMPK Controls Glucose Homeostasis and Insulin Secretion

    • AMPK Controls Lipid Metabolism

    • AMPK and Ectopic Lipid Deposition in Tissue

    • AMPK as a Regulator of White Adipose Tissue Physiology

    • AMPK Alterations in Cardiovascular Pathology

  • Management of the Metabolic Syndrome

    • Management of the Metabolic Syndrome by Exercise

    • Management of Obesity

    • Management of Lipotoxicity

    • Management of Glucose Homeostasis Alteration

    • Management of Fatty Liver

    • Management of Cardiovascular Disease

  • Conclusions and Medical Perspectives

  • References