Chapter 5. Structural Organization and Dynamics of Mitochondria in the Cells in Vivo

  1. Prof. Valdur Saks2,3,4
  1. Andrey V. Kuznetsov

Published Online: 22 NOV 2007

DOI: 10.1002/9783527621095.ch5

Molecular System Bioenergetics: Energy for Life

Molecular System Bioenergetics: Energy for Life

How to Cite

Kuznetsov, A. V. (2007) Structural Organization and Dynamics of Mitochondria in the Cells in Vivo, in Molecular System Bioenergetics: Energy for Life (ed V. Saks), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527621095.ch5

Editor Information

  1. 2

    J. Fourier University, Laboratory of Bioenergetics, 2280 rue de la Piscine, 38041 Grenoble Cedex 9, France

  2. 3

    Université Joseph Fourier, Bioénergétique Fondamentale et Appliquée, INSERM U884, BP 53X, 38041 Grenoble Cedex, France

  3. 4

    National Institute of Chemical and Biological Physics, Laboratory of Bioenergetics, Akadeemia tee 23, 12618 Tallinn, Estonia

Author Information

  1. Innsbruck Medical University, Department of General and Transplant Surgery, Daniel-Swarovski Research Laboratory, Innrain 66, 6020 Innsbruck, Austria

Publication History

  1. Published Online: 22 NOV 2007
  2. Published Print: 19 SEP 2007

ISBN Information

Print ISBN: 9783527317875

Online ISBN: 9783527621095

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Keywords:

  • molecular system bioenergetics;
  • biological oxidation;
  • organization;
  • dynamics;
  • cellular energetics;
  • mitochondria in cells in vivo;
  • mitochondrial morphology;
  • mitochondrial movement;
  • motility

Summary

This chapter contains sections titled:

  • Abstract

  • Introduction

  • Intracellular Organization of Mitochondria

    • Multiple Functions of Mitochondria in the Cells in Vivo

    • Analysis of Mitochondrial Dynamics and Intracellular Organization in Vivo: Confocal Fluorescent Microscopy

    • Mitochondrial Clusters and Subpopulations, Mitochondrial Heterogeneity, and their Physiological and Pathophysiological Roles

    • Mitochondria as Discrete Units in Highly Differentiated Cells Versus the Mitochondrial Interconnected Network

    • Role of Mitochondrial Interactions with Other Intracellular Structures for Regulating Mitochondrial and Cellular Function

    • Tissue and Cell-type Specificity of Mitochondrial Intracellular Organization and Dynamics

  • Mitochondrial Dynamics: Regulation of Mitochondrial Morphology

    • Mitochondrial Shape Proteins

    • Mitochondrial Fusion and Fission

    • Mitochondrial Fragmentation During Apoptosis

    • Apoptotic Control and Mitochondrial Dynamics

    • The Importance of Spatial Mitochondrial Organization for Mediating Lethal Ca2+ Waves

  • Mitochondrial Dynamics: Mitochondrial Movement (Motility) in the Cell

    • Key Role of the Cytoskeleton and Specific Motor and Connector Proteins for Mitochondrial Movement

    • Motility of Mitochondria in Neurons

  • Concluding Remarks

  • References