Chapter 3. Homogeneous Catalysis

  1. Dr. Gadi Rothenberg

Published Online: 3 MAR 2008

DOI: 10.1002/9783527621866.ch3

Catalysis: Concepts and Green Applications

Catalysis: Concepts and Green Applications

How to Cite

Rothenberg, G. (2008) Homogeneous Catalysis, in Catalysis: Concepts and Green Applications, Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527621866.ch3

Author Information

  1. Van't Hoff Institute for Molecular Sciences, University of Amsterdam, The Netherlands˜gadi

Publication History

  1. Published Online: 3 MAR 2008
  2. Published Print: 29 JAN 2008

ISBN Information

Print ISBN: 9783527318247

Online ISBN: 9783527621866



  • catalysis;
  • green chemistry;
  • homogeneous catalysis;
  • metal complex catalysis;
  • liquid phase;
  • homogeneous catalysis without metals;
  • click chemistry


This chapter contains sections titled:

  • Metal Complex Catalysis in the Liquid Phase

    • Elementary Steps in Homogeneous Catalysis

      • Ligand Exchange: Dissociation and Coordination

      • Oxidative Addition

      • Reductive Elimination

      • Insertion and Migration

      • De-insertion and β-Elimination

      • Nucleophilic Attack on a Coordinated Substrate

      • Other Reaction Types

    • Structure/Activity Relationships in Homogeneous Catalysis

      • Steric Effects: Ligand Size, Flexibility, and Symmetry

      • Electronic Effects of Ligands, Substrates, and Solvents

    • Asymmetric Homogeneous Catalysis

    • Industrial Examples

      • The Shell Higher Olefins Process (SHOP)

      • The Wacker Oxidation Process

      • The Du Pont Synthesis of Adiponitrile

      • The Ciba–Geigy Metolachlor Process

  • Homogeneous Catalysis without Metals

    • Classic Acid/Base Catalysis

    • Organocatalysis

  • Scaling up Homogeneous Reactions: Pros and Cons

    • Catalyst Recovery and Recycling

    • Hybrid Catalysts: Bridging the Homogeneous/Heterogeneous Gap

  • “Click Chemistry” and Homogeneous Catalysis

  • Exercises

  • References