Chapter 12. Biosynthesis and Regulation of Phenazine Compounds in Pseudomonas spp.

  1. Prof. Dr. Bernd H. A. Rehm
  1. Dmitri V. Mavrodi1,
  2. Linda S. Thomashow2 and
  3. Wulf Blankenfeldt3

Published Online: 31 MAR 2008

DOI: 10.1002/9783527622009.ch12

Pseudomonas: Model Organism, Pathogen, Cell Factory

Pseudomonas: Model Organism, Pathogen, Cell Factory

How to Cite

Mavrodi, D. V., Thomashow, L. S. and Blankenfeldt, W. (2008) Biosynthesis and Regulation of Phenazine Compounds in Pseudomonas spp., in Pseudomonas: Model Organism, Pathogen, Cell Factory (ed B. H. A. Rehm), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527622009.ch12

Editor Information

  1. Institute of Molecular BioSciences, Massey University, Private Bag 11222, Palmerston North 4442, New Zealand

Author Information

  1. 1

    Washington State University, Department of Plant Pathology, Pullman, WA 99164-6430, USA

  2. 2

    Washington State University, USDA-ARS Root Disease and Biological Control Research Unit, Pullman, WA 99164-6430, USA

  3. 3

    Max-Planck Institute of Molecular Physiology, Otto-Hahn-Str. 11, 44227 Dortmund, Germany

Publication History

  1. Published Online: 31 MAR 2008
  2. Published Print: 26 MAR 2008

ISBN Information

Print ISBN: 9783527319145

Online ISBN: 9783527622009

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Keywords:

  • phenazine compounds;
  • biosynthesis;
  • regulation;
  • diversity;
  • role;
  • Pseudomonas spp.;
  • evolution of pathways;
  • phenazine production regulation in Pseudomonas Spp.;
  • biological activity

Summary

This chapter contains sections titled:

  • Introduction

  • Diversity of Phenazine Compounds Produced by Pseudomonas spp

  • Biosynthesis of Phenazines and Evolution of Pathways

    • Core Biosynthetic Pathway and Assembly of the Phenazine Scaffold

    • Phenazine-Modifying Genes

    • Evolution of Phenazine Pathways

  • Regulation of Phenazine Production in Pseudomonas Spp.

    • Phenazine Biosynthesis and N-Acyl-Homoserine Lactone (Acyl-HSL)-Based Quorum Sensing (QS)

    • Global Regulation

  • Biological Activity and Role of Phenazine Compounds from Pseudomonas Spp.

    • Spectrum of Biological Activity of Phenazines

    • Mode of Action and Mechanisms of Self-Defense

    • Redox Homeostasis and Other Physiological Roles

  • Conclusions

  • References