Chapter 3. Adherence of Pseudomonas aeruginosa

  1. Prof. Dr. Bernd H. A. Rehm
  1. Randall T. Irvin

Published Online: 31 MAR 2008

DOI: 10.1002/9783527622009.ch3

Pseudomonas: Model Organism, Pathogen, Cell Factory

Pseudomonas: Model Organism, Pathogen, Cell Factory

How to Cite

Irvin, R. T. (2008) Adherence of Pseudomonas aeruginosa, in Pseudomonas: Model Organism, Pathogen, Cell Factory (ed B. H. A. Rehm), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527622009.ch3

Editor Information

  1. Institute of Molecular BioSciences, Massey University, Private Bag 11222, Palmerston North 4442, New Zealand

Author Information

  1. University of Alberta, Department of Medical Microbiology and Immunology, Edmonton, Alberta T6G 2H7, Canada

Publication History

  1. Published Online: 31 MAR 2008
  2. Published Print: 26 MAR 2008

ISBN Information

Print ISBN: 9783527319145

Online ISBN: 9783527622009



  • adherence;
  • Pseudomonas aeruginosa;
  • virulence;
  • surface receptor requirements;
  • pilus adhesin;
  • human mucosal surfaces;
  • X-ray crystallography;
  • structural studies;
  • pilus fiber;
  • receptor-binding domain;
  • pili as nanowires for redox reactions


This chapter contains sections titled:

  • Introduction

  • What is Adherence?

  • Role of Adherence in Infection

  • How is Bacterial Adherence Associated with Virulence?

  • P. aeruginosa Adhesions

  • Surface Receptor Requirements of the Pilus Adhesin

  • How Does PilA Mediate Attachment to Human Mucosal Surfaces?

  • X-ray Crystallographic Structural Studies of the Pilin Structural Protein

  • Structure of the Pilus Fiber

  • Structure of the Receptor-Binding Domain and Location on the Pilus

  • Structural Nature of the Receptor-Binding Domain

  • Twitching Motility

  • How Does the Pilus Attach to a Solid Surface?

  • The Monkey-Bar Swing Paradox

  • Molecular Basis for Receptor-binding Domain Interaction with Steel Surfaces

  • Pili as Nanowires for Redox Reactions

  • What is the Most Important Role of Adherence to P. aeruginosa

  • References