Chapter 10. Gap Junctions: Connexin Functions and Roles in Human Disease

  1. Prof. Dr. Susan E. LaFlamme2,
  2. Prof. Andrew P. Kowalczyk3
  1. Michael Koval

Published Online: 11 APR 2008

DOI: 10.1002/9783527622092.ch10

Book Title

Cell Junctions: Adhesion, Development, and Disease

Cell Junctions: Adhesion, Development, and Disease

Additional Information

How to Cite

Koval, M. (2008) Gap Junctions: Connexin Functions and Roles in Human Disease, in Cell Junctions: Adhesion, Development, and Disease (eds S. E. LaFlamme and A. P. Kowalczyk), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527622092.ch10

Editor Information

  1. 2

    Albany Medical College, Center for Cell Biology and Cancer Research, 47 New Scotland Avenue, Albany, NY 12208, USA

  2. 3

    Emory University School of Medicine, Departments of Cell Biology and Dermatology, 615 Michael Street, Atlanta, GA 30322, USA

Author Information

  1. Emory University School of Medicine, Department of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Atlanta, GA 30322, USA

Publication History

  1. Published Online: 11 APR 2008
  2. Published Print: 26 MAR 2008

ISBN Information

Print ISBN: 9783527318827

Online ISBN: 9783527622092

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CHAPTER TOOLS

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Keywords:

  • cell junctions;
  • gap junctions;
  • connexin functions;
  • roles in human disease;
  • connexin structure;
  • connexin assembly;
  • connexion interactions;
  • connexin binding proteins;
  • phosphorylation;
  • channel permeability;
  • signaling

Summary

This chapter contains sections titled:

  • Introduction

  • Connexin Structure and Assembly

  • Interactions Between Different Connexins

  • Connexin Binding Proteins and Phosphorylation

  • Channel Permeability and Signaling

  • Connexins in Human Disease

  • Role of Connexins in Vessel Inflammation and Atherosclerosis

  • Conclusions

  • References

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