Chapter 13. Cadherin Trafficking and Junction Dynamics

  1. Prof. Dr. Susan E. LaFlamme1,
  2. Prof. Andrew P. Kowalczyk2
  1. Christine M. Chiasson,
  2. Prof. Andrew P. Kowalczyk

Published Online: 11 APR 2008

DOI: 10.1002/9783527622092.ch13

Book Title

Cell Junctions: Adhesion, Development, and Disease

Cell Junctions: Adhesion, Development, and Disease

Additional Information

How to Cite

Chiasson, C. M. and Kowalczyk, A. P. (2008) Cadherin Trafficking and Junction Dynamics, in Cell Junctions: Adhesion, Development, and Disease (eds S. E. LaFlamme and A. P. Kowalczyk), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527622092.ch13

Editor Information

  1. 1

    Albany Medical College, Center for Cell Biology and Cancer Research, 47 New Scotland Avenue, Albany, NY 12208, USA

  2. 2

    Emory University School of Medicine, Departments of Cell Biology and Dermatology, 615 Michael Street, Atlanta, GA 30322, USA

Author Information

  1. Emory University School of Medicine, Departments of Cell Biology and Dermatology, 615 Michael Street, Atlanta, GA 30322, USA

Publication History

  1. Published Online: 11 APR 2008
  2. Published Print: 26 MAR 2008

ISBN Information

Print ISBN: 9783527318827

Online ISBN: 9783527622092

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CHAPTER TOOLS

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Keywords:

  • cell junctions;
  • cadherin trafficking;
  • junction dynamics;
  • exocytosis;
  • polarized sorting;
  • adherens junction proteins;
  • endocytosis;
  • catenin regulation;
  • Rho GTPase regulation;
  • receptor tyrosine kinase function

Summary

This chapter contains sections titled:

  • Introduction

  • Exocytosis and Polarized Sorting of Adherens Junction Proteins

  • Endocytosis of Adherens Junction Proteins

  • Catenin Regulation of Cadherin Endocytosis

  • Rho GTPase Regulation of Cadherin Endocytosis

  • Co-Regulation of Cadherin and Receptor Tyrosine Kinase Function by Endocytosis

  • Conclusions

  • Acknowledgments

  • References

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