Chapter 14. Crosstalk Between Cell–Cell and Cell–Matrix Adhesion
- Prof. Dr. Susan E. LaFlamme1,
- Prof. Andrew P. Kowalczyk2
Published Online: 11 APR 2008
DOI: 10.1002/9783527622092.ch14
Copyright © 2008 Wiley-VCH Verlag GmbH & Co. KGaA
Book Title
Cell Junctions: Adhesion, Development, and Disease
Additional Information
How to Cite
DiPersio, C. M. (2008) Crosstalk Between Cell–Cell and Cell–Matrix Adhesion, in Cell Junctions: Adhesion, Development, and Disease (eds S. E. LaFlamme and A. P. Kowalczyk), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527622092.ch14
Editor Information
- 1
Albany Medical College, Center for Cell Biology and Cancer Research, 47 New Scotland Avenue, Albany, NY 12208, USA
- 2
Emory University School of Medicine, Departments of Cell Biology and Dermatology, 615 Michael Street, Atlanta, GA 30322, USA
Publication History
- Published Online: 11 APR 2008
- Published Print: 26 MAR 2008
ISBN Information
Print ISBN: 9783527318827
Online ISBN: 9783527622092
- Summary
- Chapter
- References
Keywords:
- cell junctions;
- cell–matrix adhesion;
- cell–cell adhesion;
- crosstalk;
- integrins;
- cadherins;
- integrin–cadherin crosstalk mechanisms;
- extracellular proteolysis;
- intracellular signal transduction pathways
Summary
This chapter contains sections titled:
Introduction
Coordinate Regulation of Cell–Cell and Cell–Matrix Adhesion
Crosstalk Between Integrins and Cadherins
Mechanisms of Integrin–Cadherin Crosstalk
Extracellular Proteolysis
Cross-Regulation of Gene Expression
Changes in Intracellular Force Generation
Integrin–Cadherin Associations at Sites of Cell Adhesion
Intracellular Signal Transduction Pathways
FAK: An Integrin Effector that Signals to Cadherins
Fer: A Tyrosine Kinase that Translocates between Cadherins and Integrins
Rap1: A Central Regulator of Integrin–Cadherin Crosstalk Pathways?
The Epidermis as a Model for Investigating Cadherin–Integrin Crosstalk
Future Prospects
Acknowledgments
References