Chapter 3. The Paxillin Family and Tissue Remodeling

  1. Prof. Dr. Susan E. LaFlamme3,
  2. Prof. Andrew P. Kowalczyk4
  1. David A. Tumbarello1,
  2. Christopher E. Turner2

Published Online: 11 APR 2008

DOI: 10.1002/9783527622092.ch3

Book Title

Cell Junctions: Adhesion, Development, and Disease

Cell Junctions: Adhesion, Development, and Disease

Additional Information

How to Cite

Tumbarello, D. A. and Turner, C. E. (2008) The Paxillin Family and Tissue Remodeling, in Cell Junctions: Adhesion, Development, and Disease (eds S. E. LaFlamme and A. P. Kowalczyk), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527622092.ch3

Editor Information

  1. 3

    Albany Medical College, Center for Cell Biology and Cancer Research, 47 New Scotland Avenue, Albany, NY 12208, USA

  2. 4

    Emory University School of Medicine, Departments of Cell Biology and Dermatology, 615 Michael Street, Atlanta, GA 30322, USA

Author Information

  1. 1

    Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK

  2. 2

    SUNY Upstate Medical University, Department of Cell and Developmental Biology, 750 East Adams St., Syracuse, NY 13210, USA

Publication History

  1. Published Online: 11 APR 2008
  2. Published Print: 26 MAR 2008

ISBN Information

Print ISBN: 9783527318827

Online ISBN: 9783527622092

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CHAPTER TOOLS

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Keywords:

  • cell junctions;
  • cell–matrix junctions;
  • paxillin family;
  • tissue remodelling;
  • focal adhesions;
  • epithelial–mesenchymal transformation (EMT)

Summary

This chapter contains sections titled:

  • Focal Adhesions and the Paxillin Superfamily

    • Focal Adhesions

    • The Paxillin Superfamily

    • Structure of Paxillin

    • Structure of Hic-5

  • The Paxillin Superfamily and Tissue Remodeling

    • Epithelial–Mesenchymal Transformation

    • Integrin-Mediated Signaling and EMT

    • Paxillins α and δ in EMT

    • Hic-5 and EMT

  • References

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