Chapter 3. The Paxillin Family and Tissue Remodeling

  1. Prof. Dr. Susan E. LaFlamme3 and
  2. Prof. Andrew P. Kowalczyk4
  1. David A. Tumbarello1 and
  2. Christopher E. Turner2

Published Online: 11 APR 2008

DOI: 10.1002/9783527622092.ch3

Cell Junctions: Adhesion, Development, and Disease

Cell Junctions: Adhesion, Development, and Disease

How to Cite

Tumbarello, D. A. and Turner, C. E. (2008) The Paxillin Family and Tissue Remodeling, in Cell Junctions: Adhesion, Development, and Disease (eds S. E. LaFlamme and A. P. Kowalczyk), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527622092.ch3

Editor Information

  1. 3

    Albany Medical College, Center for Cell Biology and Cancer Research, 47 New Scotland Avenue, Albany, NY 12208, USA

  2. 4

    Emory University School of Medicine, Departments of Cell Biology and Dermatology, 615 Michael Street, Atlanta, GA 30322, USA

Author Information

  1. 1

    Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK

  2. 2

    SUNY Upstate Medical University, Department of Cell and Developmental Biology, 750 East Adams St., Syracuse, NY 13210, USA

Publication History

  1. Published Online: 11 APR 2008
  2. Published Print: 26 MAR 2008

ISBN Information

Print ISBN: 9783527318827

Online ISBN: 9783527622092

SEARCH

Keywords:

  • cell junctions;
  • cell–matrix junctions;
  • paxillin family;
  • tissue remodelling;
  • focal adhesions;
  • epithelial–mesenchymal transformation (EMT)

Summary

This chapter contains sections titled:

  • Focal Adhesions and the Paxillin Superfamily

    • Focal Adhesions

    • The Paxillin Superfamily

    • Structure of Paxillin

    • Structure of Hic-5

  • The Paxillin Superfamily and Tissue Remodeling

    • Epithelial–Mesenchymal Transformation

    • Integrin-Mediated Signaling and EMT

    • Paxillins α and δ in EMT

    • Hic-5 and EMT

  • References