Chapter 5. Integrin Trafficking
- Prof. Dr. Susan E. LaFlamme2,
- Prof. Andrew P. Kowalczyk3
Published Online: 11 APR 2008
DOI: 10.1002/9783527622092.ch5
Copyright © 2008 Wiley-VCH Verlag GmbH & Co. KGaA
Book Title
Cell Junctions: Adhesion, Development, and Disease
Additional Information
How to Cite
LaFlamme, S. E., Shi, F. and Sottile, J. (2008) Integrin Trafficking, in Cell Junctions: Adhesion, Development, and Disease (eds S. E. LaFlamme and A. P. Kowalczyk), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527622092.ch5
Editor Information
- 2
Albany Medical College, Center for Cell Biology and Cancer Research, 47 New Scotland Avenue, Albany, NY 12208, USA
- 3
Emory University School of Medicine, Departments of Cell Biology and Dermatology, 615 Michael Street, Atlanta, GA 30322, USA
Publication History
- Published Online: 11 APR 2008
- Published Print: 26 MAR 2008
ISBN Information
Print ISBN: 9783527318827
Online ISBN: 9783527622092
- Summary
- Chapter
- References
Keywords:
- cell junctions;
- cell–matrix junctions;
- integrin trafficking;
- historical perspective;
- clathrin;
- lipid rafts;
- internalization;
- occupied integrins;
- unoccupied integrins;
- integrin cytoplasmic domains;
- endocytosis of microbial pathogens;
- cell adhesion regulation;
- cell migration regulation
Summary
This chapter contains sections titled:
Introduction
Historical Perspective
Clathrin versus Lipid Rafts
Internalization of Occupied versus Unoccupied Integrins
Regulation of Integrin Trafficking
The Role of Integrin Cytoplasmic Domains
Integrin-Dependent Endocytosis of Microbial Pathogens
Regulation of Cell Adhesion and Migration by Integrin Trafficking
The Regulation of Integrin Trafficking by Cell Adhesion
Integrin Trafficking and ECM Remodeling
Conclusions
Acknowledgments
References