Chapter 15. In Vitro Methods to Assess the Biocompatibility of Plasma-Modified Surfaces

  1. Prof. Riccardo d'Agostino1,
  2. Prof. Pietro Favia1,
  3. Prof. Yoshinobu Kawai2,
  4. Prof. Hideo Ikegami3,
  5. Prof. Noriyoshi Sato4 and
  6. Prof. Farzaneh Arefi-Khonsari5
  1. M. Nardulli,
  2. R. Gristina,
  3. Prof. Riccardo d'Agostino and
  4. Prof. Pietro Favia

Published Online: 8 APR 2008

DOI: 10.1002/9783527622184.ch15

Advanced Plasma Technology

Advanced Plasma Technology

How to Cite

Nardulli, M., Gristina, R., d'Agostino, R. and Favia, P. (2007) In Vitro Methods to Assess the Biocompatibility of Plasma-Modified Surfaces, in Advanced Plasma Technology (eds R. d'Agostino, P. Favia, Y. Kawai, H. Ikegami, N. Sato and F. Arefi-Khonsari), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527622184.ch15

Editor Information

  1. 1

    Department of Chemistry, University of Bari, Via Orabona 4, 70126 Bari, Italy

  2. 2

    Research Institute for Applied Mechanics, Kyushu University, Engineering Sciences, Kasugakoen 6-1, Kasuga, Fukuoka 816-8580, Japan

  3. 3

    National Institute for Fusion Science, Toki, Gifu 509-5292, Japan

  4. 4

    Graduate School of Engineering, Tohoku University, Kadan 4-17-113, Sendai 980-0815, Japan

  5. 5

    Laboratoire de Génie des Procédés, Plasma et Traitements de Surface, Université Pierre et Marie Curie, ENSCP, 11 rue Pierre et Marie Curie, 75231 Paris cedex 05, France

Author Information

  1. Department of Chemistry, University of Bari, Via Orabona 4, 70126 Bari, Italy

Publication History

  1. Published Online: 8 APR 2008
  2. Published Print: 12 DEC 2007

ISBN Information

Print ISBN: 9783527405916

Online ISBN: 9783527622184

SEARCH

Keywords:

  • plasma-modified surfaces;
  • in vitro methods;
  • biocompatibility;
  • biomolecule immobilization;
  • cytotoxicity analysis

Summary

This chapter contains sections titled:

  • Introduction

  • Surface Modification Methods: Plasma Processes and Biomolecule Immobilization

  • In Vitro Cell Culture Tests of Artificial Surfaces

  • Cytotoxicity Analysis

    • Viability Assays

    • Metabolic Assays

    • Irritancy Assays

  • Analysis of Cell Adhesion

  • Analysis of Cell Functions

  • Conclusions