Chapter 10. Detecting Pathological Pathways of a Complex Disease by a Comparative Analysis of Networks

  1. Dr. Frank Emmert-Streib1,2 and
  2. Dr. Matthias Dehmer3
  1. Dr. Frank Emmert-Streib1,2 and
  2. Dr. Matthias Dehmer3

Published Online: 16 SEP 2008

DOI: 10.1002/9783527622818.ch10

Analysis of Microarray Data: A Network-Based Approach

Analysis of Microarray Data: A Network-Based Approach

How to Cite

Emmert-Streib, F. and Dehmer, M. (2008) Detecting Pathological Pathways of a Complex Disease by a Comparative Analysis of Networks, in Analysis of Microarray Data: A Network-Based Approach (eds F. Emmert-Streib and M. Dehmer), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527622818.ch10

Editor Information

  1. 1

    University of Washington, Department of Biostatistics, University of Washington, Department of Genome Sciences, Seattle, WA 98195-5065, USA

  2. 2

    Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA

  3. 3

    Vienna University of Technology, Discrete Mathematics and Geometry, Wiedner Hauptstrasse 8–10/104, 1040 Vienna, Austria

Author Information

  1. 1

    University of Washington, Department of Biostatistics, University of Washington, Department of Genome Sciences, Seattle, WA 98195-5065, USA

  2. 2

    Stowers Institute for Medical Research, 1000 East 50th Street, Kansas City, MO 64110, USA

  3. 3

    Vienna University of Technology, Discrete Mathematics and Geometry, Wiedner Hauptstrasse 8–10/104, 1040 Vienna, Austria

Publication History

  1. Published Online: 16 SEP 2008
  2. Published Print: 13 FEB 2008

ISBN Information

Print ISBN: 9783527318223

Online ISBN: 9783527622818

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Keywords:

  • DNA microarrays;
  • analysis;
  • detecting pathological pathways;
  • complex disease;
  • comparative analysis of networks;
  • measuring similarity of pathways;
  • chronic fatigue syndrome;
  • biological networks;
  • graph comparison

Summary

This chapter contains sections titled:

  • Introduction

  • Outline of Our Method

  • Detecting Pathological Pathways

  • Measuring the Similarity of Pathways

  • Results for the Chronic Fatigue Syndrome

  • Discussions and Conclusions

  • References