Chapter 13. Cyclopalladated Compounds as Enzyme Prototypes and Anticancer Drugs

  1. Prof. Dr. Jairton Dupont2 and
  2. Dr. Michel Pfeffer3
  1. Alexander D. Ryabov

Published Online: 16 SEP 2008

DOI: 10.1002/9783527623211.ch13

Palladacycles: Synthesis, Characterization and Applications

Palladacycles: Synthesis, Characterization and Applications

How to Cite

Ryabov, A. D. (2008) Cyclopalladated Compounds as Enzyme Prototypes and Anticancer Drugs, in Palladacycles: Synthesis, Characterization and Applications (eds J. Dupont and M. Pfeffer), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527623211.ch13

Editor Information

  1. 2

    UFRGS, Inst. of Chemistry, Lab. of Molecular Catalysis, Asv. Bento Goncalves, 9500 Porto Alegre 91501-970 RS, Brasil

  2. 3

    Université Louis Pasteur UMR 7177, Laboratoire de Synthèses Metallo-Induites, 4, rue Blaise Pascal, 67070 Strasbourg, France

Author Information

  1. Carnegie Mellon University, Department of Chemistry, 4400 Fifth Avenue, Pittsburgh, Pennsylvania 15213, USA

Publication History

  1. Published Online: 16 SEP 2008
  2. Published Print: 20 AUG 2008

ISBN Information

Print ISBN: 9783527317813

Online ISBN: 9783527623211

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Keywords:

  • anticancer drugs;
  • biomedical applications;
  • cyclopalladated compounds;
  • enzyme inhibitors;
  • hydrolase mimetics;
  • oxidoreductase mimetics

Summary

This chapter contains sections titled:

  • Introduction

  • Cyclopalladated Compounds as Mimetics of Hydrolases

  • Biologically Relevant Deoxygenation of Dimethyl Sulfoxide by Orthoplatinated Oximes: Oxidoreductase Mimetics

  • Labeling of Biological Molecules

  • Inhibitors of Enzymatic Activity

  • Medical Applications

  • References