Chapter 10. 1,25-Dihydroxyvitamin D3 and its Dissociated Analogs as Modulators of Vitamin D Receptor Action

  1. Prof. Dr. Eckhard Ottow3,
  2. Dr. Hilmar Weinmann4
  1. Ekkehard May1,
  2. Andreas Steinmeyer3,
  3. Khusru Asadullah2,
  4. Ulrich Zügel1

Published Online: 19 DEC 2008

DOI: 10.1002/9783527623297.ch10

Book Title

Nuclear Receptors as Drug Targets

Nuclear Receptors as Drug Targets

Additional Information

How to Cite

May, E., Steinmeyer, A., Asadullah, K. and Zügel, U. (2008) 1,25-Dihydroxyvitamin D3 and its Dissociated Analogs as Modulators of Vitamin D Receptor Action, in Nuclear Receptors as Drug Targets (eds E. Ottow and H. Weinmann), Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim, Germany. doi: 10.1002/9783527623297.ch10

Editor Information

  1. 3

    Bayer Schering Pharma AG, Medicinal Chemistry (S106/345), Müllerstrasse 178, 13342 Berlin, Germany

  2. 4

    Bayer Schering Pharma AG, Medicinal Chemistry (S106/048A), Müllerstrasse 178, 13342 Berlin, Germany

Author Information

  1. 1

    Bayer Schering Pharma AG, Common Mechanism Research, Early Projects, Müllerstrasse 178, 13342 Berlin, Germany

  2. 2

    Bayer Schering Pharma AG, Target Discovery, Müllerstrasse 178, 13342 Berlin, Germany

  3. 3

    Bayer Schering Pharma AG, Medicinal Chemistry (S106/345), Müllerstrasse 178, 13342 Berlin, Germany

Publication History

  1. Published Online: 19 DEC 2008
  2. Published Print: 20 AUG 2008

Book Series:

  1. Methods and Principles in Medicinal Chemistry

Book Series Editors:

  1. Prof. Dr. Raimund Mannhold5,
  2. Prof. Dr. Hugo Kubinyi6,
  3. Prof. Dr. Gerd Folkers7

Series Editor Information

  1. 5

    Molecular Drug Research Group, Heinrich-Heine-Universität, Universitätsstrasse 1, 40225 Düsseldorf, Germany

  2. 6

    Donnersbergerstrasse 9, 67256 Weisenheim am Sand, Germany

  3. 7

    Collegium Helveticum, STW/ETH Zurich, 8092 Zurich, Switzerland

ISBN Information

Print ISBN: 9783527318728

Online ISBN: 9783527623297

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CHAPTER TOOLS

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Keywords:

  • 1,25-dihydroxyvitamin D3;
  • dissociated analogs;
  • vitamin D receptor

Summary

This chapter contains sections titled:

  • Introduction

  • Principles of Cellular and Molecular Action of Vitamin D

  • Mechanisms of Vitamin D3-Mediated Immunomodulation

  • Effects of 1,25(OH)2D3In Vivo and Clinical Implications

  • Dissociated Vitamin D Derivatives

  • Calcitriol Derivatives with Heterocyclic Units in the Side-Chain

  • Conclusions

  • References

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